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- W2328479383 abstract "Synthetic biology and metabolic engineering enable generation of novel cell factories that efficiently convert renewable feedstocks into biofuels, bulk, and fine chemicals, thus creating the basis for biosustainable economy independent on fossil resources. While over a hundred proof-of-concept chemicals have been made in yeast, only a very small fraction of those has reached commercial-scale production so far. The limiting factor is the high research cost associated with the development of a robust cell factory that can produce the desired chemical at high titer, rate, and yield. Synthetic biology has the potential to bring down this cost by improving our ability to predictably engineer biological systems. This review highlights synthetic biology applications for design, assembly, and optimization of non-native biochemical pathways in baker's yeast Saccharomyces cerevisiae We describe computational tools for the prediction of biochemical pathways, molecular biology methods for assembly of DNA parts into pathways, and for introducing the pathways into the host, and finally approaches for optimizing performance of the introduced pathways." @default.
- W2328479383 created "2016-06-24" @default.
- W2328479383 creator A5035509942 @default.
- W2328479383 creator A5040605607 @default.
- W2328479383 date "2014-10-01" @default.
- W2328479383 modified "2023-10-10" @default.
- W2328479383 title "Application of synthetic biology for production of chemicals in yeast<i>Saccharomyces cerevisiae</i>" @default.
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- W2328479383 cites W1964151866 @default.
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- W2328479383 cites W1968602937 @default.
- W2328479383 cites W1970422609 @default.
- W2328479383 cites W1970893992 @default.
- W2328479383 cites W1971439989 @default.
- W2328479383 cites W1972332967 @default.
- W2328479383 cites W1973577260 @default.
- W2328479383 cites W1982249722 @default.
- W2328479383 cites W1982460474 @default.
- W2328479383 cites W1984248485 @default.
- W2328479383 cites W1987696643 @default.
- W2328479383 cites W1988992269 @default.
- W2328479383 cites W1989948255 @default.
- W2328479383 cites W1990060260 @default.
- W2328479383 cites W1990621556 @default.
- W2328479383 cites W1992043510 @default.
- W2328479383 cites W2003567369 @default.
- W2328479383 cites W2006137883 @default.
- W2328479383 cites W2018668159 @default.
- W2328479383 cites W2018750966 @default.
- W2328479383 cites W2019962216 @default.
- W2328479383 cites W2021876765 @default.
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- W2328479383 cites W2022374283 @default.
- W2328479383 cites W2022664874 @default.
- W2328479383 cites W2036559697 @default.
- W2328479383 cites W2045522994 @default.
- W2328479383 cites W2046624199 @default.
- W2328479383 cites W2050139756 @default.
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- W2328479383 cites W2078707530 @default.
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- W2328479383 doi "https://doi.org/10.1111/1567-1364.12213" @default.
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- W2328479383 hasPublicationYear "2014" @default.
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