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- W2328486571 abstract "Purpose: Everolimus-eluting stent (EES) is expected to show expeditious arterial repair due to thin struts and high biocompatibility of the copolymer. Using angioscopy (VecmovaNEO), we sought to evaluate angioscopic findings 4 months after EES implantation (XIENCE PRIME), and compared with those taken 8 months following EES (XIENCE V) implantation. Methods: Angioscopy was performed on 24 EES in consecutive 15 patients 4 months after the implantation, and on 41 EES in consecutive 28 patients 8 months after. All stents were implanted for de novo coronary artery lesions. Neointimal coverage (NIC) was graded: grade 0, stent struts exposed; grade 1, struts bulged into the lumen, although covered; grade 2, struts embedded by the neointima, but were translucently seen; grade 3, struts fully embedded and invisible. Existence of widely exposed struts (no NIC ≥30% of the stent surface area), yellow plaques (YP), and thrombus were also explored. Results: Distribution of dominant NIC grades was statistically different between 4 and 8 months (figure). Although 68% of EESs were embedded by the neointima (grade 2/3) at 8 months, 67% of EESs were not embedded (grade 0/1) at 4 months. Widely exposed struts were detected in 12% of EESs at 4 months and 10% at 8 months (P=0.90). Although YP were similarly distributed in both groups (96% at 4 months vs 78% at 8 months, P=0.08), thrombi were highly detected at 4 months than at 8 months (33% vs 7%, P=0.01). All thrombi were detected at the site of grade 0/1 NIC regardless of the follow-up period. Dominant neointimal coverage grade Dominant neointimal coverage grade Conclusions: Grade 0/1 NIC was associated with subclinical thrombus adhesion; lower NIC grades as well as thrombus adhesion decreased from 4 to 8 months, suggesting that arterial repair rapidly progressed from 4 to 8 months following EES implantation." @default.
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- W2328486571 date "2013-08-02" @default.
- W2328486571 modified "2023-09-27" @default.
- W2328486571 title "Rapid progress in arterial repair from four to eight months following everolimus-eluting stent implantation: an angioscopic observation" @default.
- W2328486571 doi "https://doi.org/10.1093/eurheartj/eht309.p3951" @default.
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