FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2328586809> ?p ?o ?g. }

• W2328586809 endingPage "3241" @default.
• W2328586809 startingPage "3229" @default.
• W2328586809 abstract "Neuronal hypersynchrony is implicated in epilepsy and other diseases. The low-frequency, spatially averaged electric fields from many thousands of neurons have been shown to promote synchrony. It remains unclear whether highly transient, spatially localized electric fields from single action potentials (ephaptic coupling) significantly affect spike timing of neighboring cells and in consequence, population synchrony. In this study, we simulated the extracellular potentials and the resulting coupling between neurons in the NEURON environment and generalized their connection rules to create an oscillator network model of a sheet of ephaptically coupled neurons. With the use of both models, we explained several aspects of epileptiform behavior not previously modeled by synaptically coupled networks. Importantly, reduction of neuron spacing induced synchronization via single-spike ephaptic coupling, agreeing with seizure suppression seen clinically and in vitro via extracellular volume adjustment. Further reduction of neuron spacing yielded locally synchronized clusters, providing a mechanism for recent in vitro observations of localized neuronal synchrony in the absence of synaptic and gap-junction coupling." @default.
• W2328586809 created "2016-06-24" @default.
• W2328586809 creator A5027981069 @default.
• W2328586809 creator A5052588728 @default.
• W2328586809 creator A5069830261 @default.
• W2328586809 date "2015-05-01" @default.
• W2328586809 modified "2023-09-25" @default.
• W2328586809 title "Computational study of synchrony in fields and microclusters of ephaptically coupled neurons" @default.
• W2328586809 cites W1555778716 @default.
• W2328586809 cites W1850752598 @default.
• W2328586809 cites W1967324141 @default.
• W2328586809 cites W1973275441 @default.
• W2328586809 cites W1974216985 @default.
• W2328586809 cites W1983634702 @default.
• W2328586809 cites W1987571899 @default.
• W2328586809 cites W2002071563 @default.
• W2328586809 cites W2004921550 @default.
• W2328586809 cites W2008263877 @default.
• W2328586809 cites W2032938771 @default.
• W2328586809 cites W2034790593 @default.
• W2328586809 cites W2038916935 @default.
• W2328586809 cites W2040585869 @default.
• W2328586809 cites W2041430383 @default.
• W2328586809 cites W2050117642 @default.
• W2328586809 cites W2052495814 @default.
• W2328586809 cites W2054016979 @default.
• W2328586809 cites W2063198621 @default.
• W2328586809 cites W2069730011 @default.
• W2328586809 cites W2078156409 @default.
• W2328586809 cites W2080929714 @default.
• W2328586809 cites W2082448915 @default.
• W2328586809 cites W2091644352 @default.
• W2328586809 cites W2107281753 @default.
• W2328586809 cites W2107566823 @default.
• W2328586809 cites W2110007355 @default.
• W2328586809 cites W2118542498 @default.
• W2328586809 cites W2131705496 @default.
• W2328586809 cites W2135266824 @default.
• W2328586809 cites W2147427684 @default.
• W2328586809 cites W2150497419 @default.
• W2328586809 cites W2151720121 @default.
• W2328586809 cites W2152350245 @default.
• W2328586809 cites W2157586156 @default.
• W2328586809 cites W2160607236 @default.
• W2328586809 cites W2163038565 @default.
• W2328586809 cites W2167809052 @default.
• W2328586809 cites W2169619863 @default.
• W2328586809 cites W2170345310 @default.
• W2328586809 cites W2170814877 @default.
• W2328586809 cites W2502209207 @default.
• W2328586809 cites W4214775604 @default.
• W2328586809 cites W4232995451 @default.
• W2328586809 doi "https://doi.org/10.1152/jn.00546.2014" @default.
• W2328586809 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/4440237" @default.
• W2328586809 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25673735" @default.
• W2328586809 hasPublicationYear "2015" @default.
• W2328586809 type Work @default.
• W2328586809 sameAs 2328586809 @default.
• W2328586809 citedByCount "13" @default.
• W2328586809 countsByYear W23285868092015 @default.
• W2328586809 countsByYear W23285868092016 @default.
• W2328586809 countsByYear W23285868092019 @default.
• W2328586809 countsByYear W23285868092020 @default.
• W2328586809 countsByYear W23285868092021 @default.
• W2328586809 countsByYear W23285868092022 @default.
• W2328586809 countsByYear W23285868092023 @default.
• W2328586809 crossrefType "journal-article" @default.
• W2328586809 hasAuthorship W2328586809A5027981069 @default.
• W2328586809 hasAuthorship W2328586809A5052588728 @default.
• W2328586809 hasAuthorship W2328586809A5069830261 @default.
• W2328586809 hasBestOaLocation W23285868092 @default.
• W2328586809 hasConcept C112592302 @default.
• W2328586809 hasConcept C121332964 @default.
• W2328586809 hasConcept C127162648 @default.
• W2328586809 hasConcept C131584629 @default.
• W2328586809 hasConcept C144024400 @default.
• W2328586809 hasConcept C149923435 @default.
• W2328586809 hasConcept C158157758 @default.
• W2328586809 hasConcept C169760540 @default.
• W2328586809 hasConcept C17077164 @default.
• W2328586809 hasConcept C185263204 @default.
• W2328586809 hasConcept C185592680 @default.
• W2328586809 hasConcept C186060115 @default.
• W2328586809 hasConcept C191897082 @default.
• W2328586809 hasConcept C192562407 @default.
• W2328586809 hasConcept C2778562939 @default.
• W2328586809 hasConcept C2778794669 @default.
• W2328586809 hasConcept C28406088 @default.
• W2328586809 hasConcept C2908647359 @default.
• W2328586809 hasConcept C41008148 @default.
• W2328586809 hasConcept C55493867 @default.
• W2328586809 hasConcept C76155785 @default.
• W2328586809 hasConcept C79879829 @default.
• W2328586809 hasConcept C86803240 @default.
• W2328586809 hasConceptScore W2328586809C112592302 @default.
• W2328586809 hasConceptScore W2328586809C121332964 @default.
• W2328586809 hasConceptScore W2328586809C127162648 @default.
• W2328586809 hasConceptScore W2328586809C131584629 @default.

• next