Matches in SemOpenAlex for { <https://semopenalex.org/work/W2328625834> ?p ?o ?g. }
- W2328625834 endingPage "S69" @default.
- W2328625834 startingPage "S68" @default.
- W2328625834 abstract "Since relapse following allogeneic hematopoietic stem cell transplantation (HSCT) can be due to the escape of the residual malignant cells from the graft-versus-leukemia (GvL) effect and given the role of NK cells in GvL and the importance of HLA-E in the modulation of NK cell function, we investigated whether polymorphisms of HLA-E molecule could impact on the incidence of relapse and the improvement of Disease-free Survival (DFS) after allogeneic HSCT. The study group included 56 pairs of donors and patients with malignant hematological disorders undergoing HLA-E matched allogeneic HSCT. The median follow-up was 43.6 (range 20.5–113.1) months. They were genotyped for HLA-E locus using a sequence-specific primer (SSP)-PCR. We found a lower incidence of relapse (p = 0.02) in the patients with HLA-E*0103/0103 genotype compared to those with other genotypes of HLA-E. We also showed an association between HLA-E*0103/0103 genotype and a better DFS (p = 0.001). Our results suggest a protective role for HLA-E*0103/0103 genotype against relapse and an association between this genotype and an improved DFS following HLA-E matched allogeneic HSCT." @default.
- W2328625834 created "2016-06-24" @default.
- W2328625834 creator A5001646221 @default.
- W2328625834 creator A5001969794 @default.
- W2328625834 creator A5007982357 @default.
- W2328625834 creator A5009243652 @default.
- W2328625834 creator A5014745384 @default.
- W2328625834 creator A5018950097 @default.
- W2328625834 creator A5019358630 @default.
- W2328625834 creator A5020116063 @default.
- W2328625834 creator A5028638054 @default.
- W2328625834 creator A5032585809 @default.
- W2328625834 creator A5037820718 @default.
- W2328625834 creator A5047998505 @default.
- W2328625834 creator A5050597176 @default.
- W2328625834 creator A5058925624 @default.
- W2328625834 creator A5059011366 @default.
- W2328625834 creator A5059361091 @default.
- W2328625834 creator A5066352955 @default.
- W2328625834 creator A5076329357 @default.
- W2328625834 creator A5076651597 @default.
- W2328625834 creator A5080330116 @default.
- W2328625834 creator A5081487269 @default.
- W2328625834 creator A5086763923 @default.
- W2328625834 creator A5090938605 @default.
- W2328625834 date "2015-04-01" @default.
- W2328625834 modified "2023-09-27" @default.
- W2328625834 title "134 ALLOGENEIC HEMATOPOIETIC STEM CELL TRANSPLANTATION IN LOWER RISK MDS PATIENTS : A RETROSPECTIVE STUDY ON BEHALF OF THE CMWP OF THE EBMT" @default.
- W2328625834 doi "https://doi.org/10.1016/s0145-2126(15)30135-1" @default.
- W2328625834 hasPublicationYear "2015" @default.
- W2328625834 type Work @default.
- W2328625834 sameAs 2328625834 @default.
- W2328625834 citedByCount "0" @default.
- W2328625834 crossrefType "journal-article" @default.
- W2328625834 hasAuthorship W2328625834A5001646221 @default.
- W2328625834 hasAuthorship W2328625834A5001969794 @default.
- W2328625834 hasAuthorship W2328625834A5007982357 @default.
- W2328625834 hasAuthorship W2328625834A5009243652 @default.
- W2328625834 hasAuthorship W2328625834A5014745384 @default.
- W2328625834 hasAuthorship W2328625834A5018950097 @default.
- W2328625834 hasAuthorship W2328625834A5019358630 @default.
- W2328625834 hasAuthorship W2328625834A5020116063 @default.
- W2328625834 hasAuthorship W2328625834A5028638054 @default.
- W2328625834 hasAuthorship W2328625834A5032585809 @default.
- W2328625834 hasAuthorship W2328625834A5037820718 @default.
- W2328625834 hasAuthorship W2328625834A5047998505 @default.
- W2328625834 hasAuthorship W2328625834A5050597176 @default.
- W2328625834 hasAuthorship W2328625834A5058925624 @default.
- W2328625834 hasAuthorship W2328625834A5059011366 @default.
- W2328625834 hasAuthorship W2328625834A5059361091 @default.
- W2328625834 hasAuthorship W2328625834A5066352955 @default.
- W2328625834 hasAuthorship W2328625834A5076329357 @default.
- W2328625834 hasAuthorship W2328625834A5076651597 @default.
- W2328625834 hasAuthorship W2328625834A5080330116 @default.
- W2328625834 hasAuthorship W2328625834A5081487269 @default.
- W2328625834 hasAuthorship W2328625834A5086763923 @default.
- W2328625834 hasAuthorship W2328625834A5090938605 @default.
- W2328625834 hasConcept C104317684 @default.
- W2328625834 hasConcept C120665830 @default.
- W2328625834 hasConcept C121332964 @default.
- W2328625834 hasConcept C126322002 @default.
- W2328625834 hasConcept C135763542 @default.
- W2328625834 hasConcept C143998085 @default.
- W2328625834 hasConcept C147483822 @default.
- W2328625834 hasConcept C188280979 @default.
- W2328625834 hasConcept C203014093 @default.
- W2328625834 hasConcept C2777408962 @default.
- W2328625834 hasConcept C28328180 @default.
- W2328625834 hasConcept C2911091166 @default.
- W2328625834 hasConcept C54355233 @default.
- W2328625834 hasConcept C61511704 @default.
- W2328625834 hasConcept C71924100 @default.
- W2328625834 hasConcept C86803240 @default.
- W2328625834 hasConcept C90924648 @default.
- W2328625834 hasConceptScore W2328625834C104317684 @default.
- W2328625834 hasConceptScore W2328625834C120665830 @default.
- W2328625834 hasConceptScore W2328625834C121332964 @default.
- W2328625834 hasConceptScore W2328625834C126322002 @default.
- W2328625834 hasConceptScore W2328625834C135763542 @default.
- W2328625834 hasConceptScore W2328625834C143998085 @default.
- W2328625834 hasConceptScore W2328625834C147483822 @default.
- W2328625834 hasConceptScore W2328625834C188280979 @default.
- W2328625834 hasConceptScore W2328625834C203014093 @default.
- W2328625834 hasConceptScore W2328625834C2777408962 @default.
- W2328625834 hasConceptScore W2328625834C28328180 @default.
- W2328625834 hasConceptScore W2328625834C2911091166 @default.
- W2328625834 hasConceptScore W2328625834C54355233 @default.
- W2328625834 hasConceptScore W2328625834C61511704 @default.
- W2328625834 hasConceptScore W2328625834C71924100 @default.
- W2328625834 hasConceptScore W2328625834C86803240 @default.
- W2328625834 hasConceptScore W2328625834C90924648 @default.
- W2328625834 hasLocation W23286258341 @default.
- W2328625834 hasOpenAccess W2328625834 @default.
- W2328625834 hasPrimaryLocation W23286258341 @default.
- W2328625834 hasRelatedWork W1565849830 @default.
- W2328625834 hasRelatedWork W2013028547 @default.
- W2328625834 hasRelatedWork W2104825820 @default.
- W2328625834 hasRelatedWork W2185033940 @default.