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- W2328689110 abstract "[Mn(CO)5Br] reacts with cysteamine and 4-amino-thiophenyl with a ratio of 2:3 in refluxing tetrahydrofuran to the complexes of the type [{(OC)3Mn}2(μ-SCH2CH2NH3)3]Br2 (1, CORM-EDE1) and [{(OC)3Mn}2(μ-SC6H4-4-NH3)3]Br2 (2, CORM-EDE2). Compound 2 precipitates during refluxing of the tetrahydrofuran solution as a yellow solid whereas 1 forms a red oil that slowly solidifies. Recrystallization of 2 from water yields the HBr-free complex [{(OC)3Mn}2(μ-S-C6H4-4-NH2)2(μ-SC6H4-4-NH3)] (3). The n-propylthiolate ligand (which is isoelectronic to the bridging thiolate of 1) leads to the formation of the di- and tetranuclear complexes [(OC)4Mn(μ-S-nPr)2]2 and [(OC)3Mn(μ-S-nPr)]4. CORM-EDE1 possesses ideal properties to administer carbon monoxide to biological and medicinal tissues upon irradiation (photoCORM). Isolated crystalline CORM-EDE1 can be handled at ambient and aerobic conditions. This complex is nontoxic, highly soluble in water, and indefinitely stable therein in the absence of air and phosphate buffer. CORM-EDE1 is stable as frozen stock in aqueous solution without any limitations, and these stock solutions maintain their CO release properties. The reducing dithionite does not interact with CORM-EDE1, and therefore, the myoglobin assay represents a valuable tool to study the release kinetics of this photoCORM. After CO liberation, the formation of MnHPO4 in aqueous buffer solution can be verified." @default.
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- W2328689110 date "2015-12-16" @default.
- W2328689110 modified "2023-10-10" @default.
- W2328689110 title "CORM-EDE1: A Highly Water-Soluble and Nontoxic Manganese-Based photoCORM with a Biogenic Ligand Sphere" @default.
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- W2328689110 cites W1539796472 @default.
- W2328689110 cites W1586245747 @default.
- W2328689110 cites W1646252448 @default.
- W2328689110 cites W1939352300 @default.
- W2328689110 cites W1966099448 @default.
- W2328689110 cites W1969930587 @default.
- W2328689110 cites W1970318581 @default.
- W2328689110 cites W1976254490 @default.
- W2328689110 cites W1976639823 @default.
- W2328689110 cites W1977311648 @default.
- W2328689110 cites W1978629989 @default.
- W2328689110 cites W1978928420 @default.
- W2328689110 cites W1979368277 @default.
- W2328689110 cites W1980431646 @default.
- W2328689110 cites W1985635711 @default.
- W2328689110 cites W1988749195 @default.
- W2328689110 cites W1993130948 @default.
- W2328689110 cites W2000422315 @default.
- W2328689110 cites W2000970736 @default.
- W2328689110 cites W2011031473 @default.
- W2328689110 cites W2012836808 @default.
- W2328689110 cites W2017702218 @default.
- W2328689110 cites W2018881354 @default.
- W2328689110 cites W2021487655 @default.
- W2328689110 cites W2022086508 @default.
- W2328689110 cites W2030682582 @default.
- W2328689110 cites W2031180465 @default.
- W2328689110 cites W2041701905 @default.
- W2328689110 cites W2043065633 @default.
- W2328689110 cites W2046918505 @default.
- W2328689110 cites W2047229290 @default.
- W2328689110 cites W2048549466 @default.
- W2328689110 cites W2049434003 @default.
- W2328689110 cites W2049800847 @default.
- W2328689110 cites W2051987011 @default.
- W2328689110 cites W2052055333 @default.
- W2328689110 cites W2055159418 @default.
- W2328689110 cites W2056016033 @default.
- W2328689110 cites W2065372600 @default.
- W2328689110 cites W2070087900 @default.
- W2328689110 cites W2070799904 @default.
- W2328689110 cites W2073527679 @default.
- W2328689110 cites W2086945873 @default.
- W2328689110 cites W2093069478 @default.
- W2328689110 cites W2094162566 @default.
- W2328689110 cites W2095583294 @default.
- W2328689110 cites W2098817182 @default.
- W2328689110 cites W2124433916 @default.
- W2328689110 cites W2130237005 @default.
- W2328689110 cites W2131125415 @default.
- W2328689110 cites W2131350133 @default.
- W2328689110 cites W2135902647 @default.
- W2328689110 cites W2137788649 @default.
- W2328689110 cites W2145538332 @default.
- W2328689110 cites W2165613958 @default.
- W2328689110 cites W2166154919 @default.
- W2328689110 cites W2171108386 @default.
- W2328689110 cites W2313209431 @default.
- W2328689110 cites W2331419692 @default.
- W2328689110 cites W2333045293 @default.
- W2328689110 cites W2036607976 @default.
- W2328689110 doi "https://doi.org/10.1021/acs.inorgchem.5b01904" @default.
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