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- W2328702993 abstract "Sex ChromosomeThe mammalian Y chromosome encodes a specialized set of genes that are essential for male viability and fertility. In particular, the sex-determining region Y (SRY) protein is necessary to initiate male sex determination. However, Yamauchi et al. show that the functions of the entire Y chromosome can be replaced with only two genes. In mice, two transgenes, Sox9 and Eif2s3x , compensated for the absence of all Y chromosome genes to allow successful sperm formation.Science , this issue p. [514][1] [1]: /lookup/doi/10.1126/science.aad1795" @default.
- W2328702993 created "2016-06-24" @default.
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- W2328702993 date "2016-01-28" @default.
- W2328702993 modified "2023-09-24" @default.
- W2328702993 title "Replacing the Y chromosome" @default.
- W2328702993 doi "https://doi.org/10.1126/science.351.6272.461-f" @default.
- W2328702993 hasPublicationYear "2016" @default.
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