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- W2328851966 abstract "Increased skeletal loading leads to increased bone mass as shown by several animal studies (Savifle et al. 1969, Clin Orth Relat Res 65,81 -88; Chen et al. 1994 Bone 15,313-319). Skeletal loading is influenced by weight and muscle contractions. We examined the relationship between grip strength and bone mineral density (BMD) in a cohort of 616 healthy older men resident in Cambridge. AH subjects completed a questionnaire and BMDs of hip and lumbar spine (LS) were obtained using dual x-ray absorptiometry. Muscle grip strength was measured twice in each hand. The average of the two grip strengths was used in the subsequent analysis. Mean(sd) age was 69.7(3.4) years, age range 65-76. 557 (92%) reported the right hand as dominant. Men in the highest fertile of grip strength in both hands were significantly younger, heavier and taller. Left and right hand grip strength were highly correlated (r =+0.78 p<0.0001). Grip strength was correlated with physical activity (r =+0.13 p<0.001), age (r =-0.25 pO.OOOl) and weight (r =+0.24 p<0.0001). Crude correlations of grip strength with BMD were significant at all sites but age and weight adjusted grip strength was correlated to BMD at the trochanter only (r =+0.10 p<0.001). Unadjusted BMD by tertiles of grip strength increased with increasing grip strength in both hands and at all sites in a stepwise association. Age and weight adjusted BMD the trend persisted but was significant only at the trochanter in the dominant hand (p=0.04). Excluding men with self-reported arthritis or those on medications, did not aher the relationship. Grip strength in both the dominant and nondommant hands is positively correlated to BMD at all shes. This correlation remained significant only at the trochanter in the dominant hand after age and weight adjustment." @default.
- W2328851966 created "2016-06-24" @default.
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- W2328851966 date "1997-01-01" @default.
- W2328851966 modified "2023-09-27" @default.
- W2328851966 title "Osteoporosis Assessment: Validation of Bone Ultrasound for Use in the Elderly" @default.
- W2328851966 doi "https://doi.org/10.1093/ageing/26.suppl_1.p38-b" @default.
- W2328851966 hasPublicationYear "1997" @default.
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