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• W2328909167 abstract "As part of our continuing chemical and biological analyses of Rubiaceae species from Cerrado, we isolated novel alkaloids <b>1</b> and <b>2</b>, along with known compounds epicatechin, ursolic acid, and oleanolic acid, from <i>Galianthe ramosa</i>. Alkaloid <b>2</b> inhibited malate synthase from the pathogenic fungus <i>Paracoccidioides</i> spp. This enzyme is considered an important molecular target because it is not found in humans. Molecular docking simulations were used to describe the interactions between the alkaloids and malate synthase." @default.
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• W2328909167 date "2014-11-20" @default.
• W2328909167 modified "2023-10-01" @default.
• W2328909167 title "β-Carboline Alkaloids from Galianthe ramosa Inhibit Malate Synthase from Paracoccidioides spp." @default.
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• W2328909167 doi "https://doi.org/10.1055/s-0034-1383305" @default.
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