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- W2328952493 abstract "Abstract Rhodiola rosea is a Russian and Chinese medicinal plant used in medical practice as a stimulating, adaptogenic and antiarrhythmic agent. Many investigations have pointed to the anticancer and antimutagenic role of R. rosea. In spite of these therapeutic effects of R. rosea extract. little is known about the mechanism of its anticancer action, because few cytological investigations havebeen conducted on the mitotic activity, cellular cycle, structure, ultrastructure, and cytophysiology of both animal and plant cells treated with the extract. Our studies have shown that extract from R. rosea roots (containing rosavine and cinnamyl alcohol) cause the inhibition of a mitotic activity; however, cells resume their divisions after the postincubation period. During incubation in the extract, accumulation of G2/M cells was observed. Chromosomes inprophase and metaphase were shorter and thicker but the extract did not cause chromosomal aberrations or the formation of micronuclei. Ultrastructure changes aft..." @default.
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- W2328952493 date "2003-01-01" @default.
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- W2328952493 title "Antimitotic effect, G2/M accumulation, chromosomal and ultrastructure changes in meristematic cells of<i>Allium cepa</i>L. root tips treated with the extract from<i>Rhodiola rosea</i>roots" @default.
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- W2328952493 doi "https://doi.org/10.1080/00087114.2003.10589343" @default.
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