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- W2329127574 abstract "Nonalcoholic fatty liver disease (NAFLD) is an emerging hepatic disorder both in males and females of Asian countries mainly linked with high fat diet (HFD) consumption. The purpose behind the current project was to assess the counter effect of fat reducing agents against HFD induced fibrosis. Forty males (M) and forty female (F) Rattus norvegicus were subdivided into four groups (0, I, II and III) depending upon different diet compositions. Group 0 was fed on 100% rat chow, Groups I, II and III were provided with HFD. The diets of group II and III were supplemented with 5% Nigella sativa seeds or Plantago ovata husks per kg of HFD respectively. The histopathology of livers revealed portal and peri cellular fibrosis in M-I and F-I groups. M-II had radiating fibrosis in portal areas in comparison with F-II group while peri lobular fibrosis bridging among portal triades was evident in the M-III and F-III groups. It is concluded that livers of males were more susceptible to HFD induced fibrosis. N. sativa seeds were helpful to minimize fibrosis while P. ovata husks along with HFD induced advanced fibrosis of the liver." @default.
- W2329127574 created "2016-06-24" @default.
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- W2329127574 date "2015-01-16" @default.
- W2329127574 modified "2023-09-27" @default.
- W2329127574 title "Gender linked counter effect of N. sativa seeds and P. ovata husks on fibrosis in NAFLD" @default.
- W2329127574 doi "https://doi.org/10.1055/s-0034-1397061" @default.
- W2329127574 hasPublicationYear "2015" @default.
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