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- W2329153704 abstract "Theamyloiddeposits in21renalbiopsy specimens were subjected to a detailed immunohistochemical analysis usinga panelofantibodies againstrecognised constituents oftissue amyloid. Thiswas a retrospective studyofmaterial originallysubmittedduringtheinvestigation of various renalabnormalities and studiedby a routineprotocol including histochemistry, electronmicroscopy, andimmunofluorescence. The presence ofan amyloidwas confirmedinall21 cases.Seventeen casescontained P componentand eitheramyloidA (AA)(11 cases) or an immunoglobulin light chain associated amyloid(sixcases). Four cases contained amyloidmaterialwith unusualimmunohistochemical findings; one case hadAA andP-component(PC) intheinterstitium, one case hadAlight chainand 1-2microglobulin, one case had K light chainandClq,andone case hadAlight chainsonly. Itwas possible, therefore, to identify precisely theamyloidconstituents and thereby typetheamyloidbyimmunohistochemical means. Theavailability of theantibodies usedandtheirapplication usingthesetechniques couldsimplify the confirmation of clinically suspected amyloidosis." @default.
- W2329153704 created "2016-06-24" @default.
- W2329153704 creator A5027801120 @default.
- W2329153704 date "1991-01-01" @default.
- W2329153704 modified "2023-09-27" @default.
- W2329153704 title "Immunohistological characterisation ofamyloid deposits inrenal biopsy specimens" @default.
- W2329153704 cites W2258378870 @default.
- W2329153704 hasPublicationYear "1991" @default.
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