FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2329181007> ?p ?o ?g. }

• W2329181007 endingPage "2203" @default.
• W2329181007 startingPage "2199" @default.
• W2329181007 abstract "Caspases are a family of cysteine proteases that are well-known for their roles in apoptosis and inflammation. Recent studies provide evidence that caspases are also integral to many additional cellular processes, such as differentiation and proliferation. Likewise, aberrant caspase activity has been implicated in the progression of several diseases, including neurodegenerative disorders, cancer, cardiovascular disease, and sepsis. These observations establish the importance of caspases to a diverse array of physiological functions and future endeavors will undoubtedly continue to elucidate additional processes that require caspase activity. Unfortunately, the existence of 11 functional human caspases, with overlapping substrate specificities, confounds the ability to confidently assign one or more isoforms to biological phenomena. Herein, we characterize a first-in-class FRET substrate that is selectively recognized by active caspase-3 over other initiator and executioner caspases. We further apply this substrate to specifically image caspase-3 activity in live cells undergoing apoptosis." @default.
• W2329181007 created "2016-06-24" @default.
• W2329181007 creator A5012051565 @default.
• W2329181007 creator A5017545515 @default.
• W2329181007 creator A5061479270 @default.
• W2329181007 date "2014-08-20" @default.
• W2329181007 modified "2023-09-28" @default.
• W2329181007 title "Discovery of a Highly Selective Caspase-3 Substrate for Imaging Live Cells" @default.
• W2329181007 cites W1539741413 @default.
• W2329181007 cites W1964581938 @default.
• W2329181007 cites W1968423671 @default.
• W2329181007 cites W1970724938 @default.
• W2329181007 cites W1983439962 @default.
• W2329181007 cites W1998778991 @default.
• W2329181007 cites W1999153033 @default.
• W2329181007 cites W1999891600 @default.
• W2329181007 cites W2003702237 @default.
• W2329181007 cites W2008877139 @default.
• W2329181007 cites W2013069561 @default.
• W2329181007 cites W2016157395 @default.
• W2329181007 cites W2016568695 @default.
• W2329181007 cites W2021493237 @default.
• W2329181007 cites W2024105041 @default.
• W2329181007 cites W2034891521 @default.
• W2329181007 cites W2035835337 @default.
• W2329181007 cites W2043310375 @default.
• W2329181007 cites W2045563337 @default.
• W2329181007 cites W2053801110 @default.
• W2329181007 cites W2062894160 @default.
• W2329181007 cites W2065518020 @default.
• W2329181007 cites W2084399139 @default.
• W2329181007 cites W2087367624 @default.
• W2329181007 cites W2087567974 @default.
• W2329181007 cites W2092577537 @default.
• W2329181007 cites W2094265468 @default.
• W2329181007 cites W2101546833 @default.
• W2329181007 cites W2112322230 @default.
• W2329181007 cites W2121134942 @default.
• W2329181007 cites W2135732941 @default.
• W2329181007 cites W2145327037 @default.
• W2329181007 cites W2156179144 @default.
• W2329181007 cites W2332533981 @default.
• W2329181007 doi "https://doi.org/10.1021/cb500586p" @default.
• W2329181007 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25133295" @default.
• W2329181007 hasPublicationYear "2014" @default.
• W2329181007 type Work @default.
• W2329181007 sameAs 2329181007 @default.
• W2329181007 citedByCount "27" @default.
• W2329181007 countsByYear W23291810072015 @default.
• W2329181007 countsByYear W23291810072016 @default.
• W2329181007 countsByYear W23291810072017 @default.
• W2329181007 countsByYear W23291810072018 @default.
• W2329181007 countsByYear W23291810072019 @default.
• W2329181007 countsByYear W23291810072020 @default.
• W2329181007 countsByYear W23291810072022 @default.
• W2329181007 countsByYear W23291810072023 @default.
• W2329181007 crossrefType "journal-article" @default.
• W2329181007 hasAuthorship W2329181007A5012051565 @default.
• W2329181007 hasAuthorship W2329181007A5017545515 @default.
• W2329181007 hasAuthorship W2329181007A5061479270 @default.
• W2329181007 hasConcept C163421366 @default.
• W2329181007 hasConcept C181199279 @default.
• W2329181007 hasConcept C182220744 @default.
• W2329181007 hasConcept C185592680 @default.
• W2329181007 hasConcept C190283241 @default.
• W2329181007 hasConcept C2779201268 @default.
• W2329181007 hasConcept C31573885 @default.
• W2329181007 hasConcept C55493867 @default.
• W2329181007 hasConcept C86803240 @default.
• W2329181007 hasConcept C95444343 @default.
• W2329181007 hasConcept C98424977 @default.
• W2329181007 hasConceptScore W2329181007C163421366 @default.
• W2329181007 hasConceptScore W2329181007C181199279 @default.
• W2329181007 hasConceptScore W2329181007C182220744 @default.
• W2329181007 hasConceptScore W2329181007C185592680 @default.
• W2329181007 hasConceptScore W2329181007C190283241 @default.
• W2329181007 hasConceptScore W2329181007C2779201268 @default.
• W2329181007 hasConceptScore W2329181007C31573885 @default.
• W2329181007 hasConceptScore W2329181007C55493867 @default.
• W2329181007 hasConceptScore W2329181007C86803240 @default.
• W2329181007 hasConceptScore W2329181007C95444343 @default.
• W2329181007 hasConceptScore W2329181007C98424977 @default.
• W2329181007 hasFunder F4320312995 @default.
• W2329181007 hasIssue "10" @default.
• W2329181007 hasLocation W23291810071 @default.
• W2329181007 hasLocation W23291810072 @default.
• W2329181007 hasOpenAccess W2329181007 @default.
• W2329181007 hasPrimaryLocation W23291810071 @default.
• W2329181007 hasRelatedWork W119975303 @default.
• W2329181007 hasRelatedWork W1585074713 @default.
• W2329181007 hasRelatedWork W1670069535 @default.
• W2329181007 hasRelatedWork W2048762049 @default.
• W2329181007 hasRelatedWork W2055506415 @default.
• W2329181007 hasRelatedWork W2066915710 @default.
• W2329181007 hasRelatedWork W2389372423 @default.
• W2329181007 hasRelatedWork W2931523797 @default.
• W2329181007 hasRelatedWork W4200430624 @default.
• W2329181007 hasRelatedWork W2920273130 @default.

• next