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• W2329413138 abstract "Heart rate (HR) has been linked to cardiovascular disease (CVD) and overall mortality. In a recent study, elevated HR was significantly associated with metabolic syndrome (MetSyn) (Rogowski et al., 2009). We assessed whether a high resting HR was significantly related to the presence of MetSyn in a previously established Newfoundland cohort. A random and representative sample of Newfoundland men and women who participated in a CVD prevention trial (1991-1993) was analyzed using a cross-sectional design. MetSyn was diagnosed according to the 2009 harmonized definition for MetSyn (Alberti et al., 2009). A resting HR of 75 beats per minute (bpm) or higher was considered as the cutpoint for elevated HR. Those with a history of CVD or missing MetSyn criteria were excluded from the present study. Group differences were first compared using t-test (continuous variables) and Chi-square analysis (categorical date). Logistic regression was then performed to obtain odds ratios (OR) and 95% confidence intervals (CI) for the presence of MetSyn based on two models: Model 1 - HR; and Model 2 - Model 1 plus the covariables age, sex, LDL-cholesterol, diabetes, smoking and exercise. A P value of 0.05 was set as the level of significance. A total of 622 respondents were included in the study, of which 46.3% were male and the average age 46.3 yrs ± 8.7. The prevalence of MetSyn was 43.7% in the overall sample. The average HR was 78.0 bpm ± 10.6 among those with MetSyn and 74.5 bpm ± 10.6 in those without the syndrome (P < 0.001). A larger proportion of individuals in the MetSyn group were classified as having an elevated resting HR (≥75 bpm) compared to the non-MetSyn group (62.5% vs. 48.9%; P < 0.001). In unadjusted regression analysis, individuals with high HR had a 1.75-fold increased risk of having MetSyn (95% CI, 1.26-2.41; P = 0.001). Raised HR remained a significant risk factor for the presence of MetSyn in multivariate analysis (OR, 1.82; 95% CI, 1.30-2.56; P = 0.001). Our study confirms previous findings which have reported a significant relationship between elevated HR and the presence of MetSyn. We suggest that assessing resting HR, a quick and inexpensive measurement to perform, in those with MetSyn may enhance the detection of individuals at increased CVD risk." @default.
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• W2329413138 date "2011-09-01" @default.
• W2329413138 modified "2023-09-25" @default.
• W2329413138 title "313 Does increased resting heart rate among individuals with metabolic syndrome enhance the prediction of CVD risk? An analysis of a Newfoundland population cohort" @default.
• W2329413138 doi "https://doi.org/10.1016/j.cjca.2011.07.239" @default.
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