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- W2329534657 abstract "Abstract Horizontal cells of the vertebrate retina have large receptive fields as a result of extensive gap junction coupling. Increased ambient illumination reduces horizontal cell receptive field size. Using the isolated goldfish retina, we have assessed the contribution of nitric oxide to the light-dependent reduction of horizontal cell receptive field size. Horizontal cell receptive field size was assessed by comparing the responses to centered spot and annulus stimuli and from the responses to translated slit stimuli. A period of steady illumination decreased the receptive field size of horizontal cells, as did treatment with the nitric oxide donor (Z)-1-[N-(2-aminoethyl)-N-(2-ammonioethyl)amino]diazen-1-ium-1,2-diolate (100 μ M). Blocking the endogenous production of nitric oxide with the nitric oxide synthase inhibitor, N G -nitro- l -arginine methyl ester (1 mM), decreased the light-induced reduction of horizontal cell receptive field size. These findings suggest that nitric oxide is involved in light-induced reduction of horizontal cell receptive field size." @default.
- W2329534657 created "2016-06-24" @default.
- W2329534657 creator A5026914217 @default.
- W2329534657 creator A5029629294 @default.
- W2329534657 date "2011-02-16" @default.
- W2329534657 modified "2023-10-16" @default.
- W2329534657 title "The light-induced reduction of horizontal cell receptive field size in the goldfish retina involves nitric oxide" @default.
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- W2329534657 doi "https://doi.org/10.1017/s0952523810000490" @default.
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