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• W2329593278 abstract "Purpose: The aim of the Pol-Fokus study was to evaluate factors related to uncontrolled and resistant hypertension (HT) in a large sample of treated hypertensive subjects. Methods: In the cross-sectional questionnaire-based observational study we included 12436 patients (mean age 64,0±12,3 years; range 18-98 years; 59% F, 41% M, diabetes 22,3%, coronary artery disease 44,2%) attending to general practitioner (GP) or cardiologist. To be included patients had to be ≥ 18 years old and treated for at least 12 months with antihypertensive drugs. Blood pressure (BP) was measured twice in a seated position and mean value was calculated. We defined HT control as BP both < 140 mm Hg for systolic and < 90 mm Hg for diastolic blood pressure. Among patients with uncontrolled HT we separated patients with resistant HT (RHT) defined as uncontrolled HT despite using 3 antihypertensive drugs including diuretic. We analyzed following clinical parameters: abdominal obesity (waist circumference > 102 cm in M and > 88 cm in F), eGFR (acc. to MDRD formula) and LDL cholesterol (well controlled: LDL < 2,5 mmol/L in patients with DM or known cardiovascular disease and <3,0 mmol/L in the remaining patients). Results: Among studied patients 5857 had controlled HT (47,3%), 3458 uncontrolled (27,9%) and 3060 RHT (24,7%). There were no differences in gender distribution across the groups. The frequency of uncontrolled HT and RHT differed across the age groups: <40 years (35,3%; 12,8%); 40-65 years (30,3%; 21,8%) and >65 years (25,4%; 28,1%; p<0,001) and among patients attending cardiologist (23,4%; 29,8%) or GPs (29,6%; 22,8%; p<0,001). Patients with RHT were characterized by higher frequency of abdominal obesity as compared with the controlled and uncontrolled HT patients. Patients with eGFR <60 ml/min/1,73m2 were characterized by higher frequency of RHT (31,9%) as compared with patients with eGFR 60-89 and ≥90 (25,1% and 20,8%) respectively. Among patients treated with statin the frequency of LDL cholesterol control was lower in patients with RHT and uncontrolled HT as compared with controlled ones (36,3% and 35,4% vs. 49,2%; p<0,001). Patients with diabetes, coronary artery disease and cerebrovascular disease were characterized by higher frequency of RHT as compared to patients without these disease (32,5% vs. 22,6%; p<0,001, 31,5% vs. 19,7%; p<0,001; 33,3% vs. 23,6%; p<0,001). Conclusion: Our results showed that 28% and 25% of HT patients treated for at least one year had uncontrolled HT and RHT, respectively. Both groups were characterized by higher cardiovascular risk, which was most pronounced in RHT." @default.
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• W2329593278 date "2013-08-02" @default.
• W2329593278 modified "2023-10-18" @default.
• W2329593278 title "Characteristics of uncontrolled and resistant hypertensive patients treated by general practitioners and cardiologists in Poland - Polfokus study" @default.
• W2329593278 doi "https://doi.org/10.1093/eurheartj/eht308.p1425" @default.
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