Matches in SemOpenAlex for { <https://semopenalex.org/work/W2329603014> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W2329603014 abstract "A B S T R A C T Studies of the possibility that thyroxine (T4) is converted to 3,5,3'-triiodo-L-thyronine (T3) in the extrathyroidal tissues in man have been conducted in 13 patients, all but two of whom were athyreotic or hypothyroid, and all of whom were receiving at least physiological replacement doses of synthetic sodium-Lthyroxine. T3 was found in the sera of all patients, in concentrations ranging between 243 and 680 ng/100 ml (normal range 170-270 ng/100 ml). These concentrations were far in excess of those which would have been expected on the basis of the T3 contamination of the administered T4, as measured by the same technique employed in the analysis of serum. When oral medication was enriched with 'I-labeled T4 for 8 or more days, labeled T3 and tetraiodothyroacetic acid (Tetrac or TA4) were found in the serum to the extent of approximately 2-5% of total radioactivity, as assessed by unidimensional paper chromatography. The same results were obtained with a specially purified lot of radioactive T4 containing less than 0.1% T3 as a contaminant. The identities of the 'I-labeled T3 and TA4 were verified by two-dimensional chromatography as well as by specific patterns of binding in serum. The labeled T3 isolated was bound by albumin and by T4-binding globulin (TBG), but not by T4-binding prealbumin (TBPA); in contrast the labeled TA4 was bound by albumin and TBPA, but not by TBG." @default.
- W2329603014 created "2016-06-24" @default.
- W2329603014 creator A5091065594 @default.
- W2329603014 date "1970-01-01" @default.
- W2329603014 modified "2023-09-27" @default.
- W2329603014 title "in Athyreotic Human Subjects" @default.
- W2329603014 cites W187320011 @default.
- W2329603014 cites W1970798295 @default.
- W2329603014 cites W1970871311 @default.
- W2329603014 cites W1979904200 @default.
- W2329603014 cites W1980606541 @default.
- W2329603014 cites W1987923348 @default.
- W2329603014 cites W1990550978 @default.
- W2329603014 cites W1994463804 @default.
- W2329603014 cites W2022350011 @default.
- W2329603014 cites W2023166886 @default.
- W2329603014 cites W2031451843 @default.
- W2329603014 cites W2032638297 @default.
- W2329603014 cites W2041160265 @default.
- W2329603014 cites W2050126351 @default.
- W2329603014 cites W2054877987 @default.
- W2329603014 cites W2056664245 @default.
- W2329603014 cites W2057733647 @default.
- W2329603014 cites W2065510063 @default.
- W2329603014 cites W2073488093 @default.
- W2329603014 cites W2078292462 @default.
- W2329603014 cites W2080806531 @default.
- W2329603014 cites W2083486660 @default.
- W2329603014 cites W2085772349 @default.
- W2329603014 cites W2095811126 @default.
- W2329603014 cites W2136474622 @default.
- W2329603014 cites W2162840506 @default.
- W2329603014 cites W2165670253 @default.
- W2329603014 cites W2320876785 @default.
- W2329603014 cites W2326109190 @default.
- W2329603014 cites W2335485595 @default.
- W2329603014 cites W2341254846 @default.
- W2329603014 cites W2437952995 @default.
- W2329603014 cites W2442403000 @default.
- W2329603014 hasPublicationYear "1970" @default.
- W2329603014 type Work @default.
- W2329603014 sameAs 2329603014 @default.
- W2329603014 citedByCount "5" @default.
- W2329603014 crossrefType "journal-article" @default.
- W2329603014 hasAuthorship W2329603014A5091065594 @default.
- W2329603014 hasConcept C121157162 @default.
- W2329603014 hasConcept C126322002 @default.
- W2329603014 hasConcept C134018914 @default.
- W2329603014 hasConcept C178790620 @default.
- W2329603014 hasConcept C185592680 @default.
- W2329603014 hasConcept C2776125364 @default.
- W2329603014 hasConcept C43617362 @default.
- W2329603014 hasConcept C537181965 @default.
- W2329603014 hasConcept C55493867 @default.
- W2329603014 hasConcept C71924100 @default.
- W2329603014 hasConcept C86803240 @default.
- W2329603014 hasConceptScore W2329603014C121157162 @default.
- W2329603014 hasConceptScore W2329603014C126322002 @default.
- W2329603014 hasConceptScore W2329603014C134018914 @default.
- W2329603014 hasConceptScore W2329603014C178790620 @default.
- W2329603014 hasConceptScore W2329603014C185592680 @default.
- W2329603014 hasConceptScore W2329603014C2776125364 @default.
- W2329603014 hasConceptScore W2329603014C43617362 @default.
- W2329603014 hasConceptScore W2329603014C537181965 @default.
- W2329603014 hasConceptScore W2329603014C55493867 @default.
- W2329603014 hasConceptScore W2329603014C71924100 @default.
- W2329603014 hasConceptScore W2329603014C86803240 @default.
- W2329603014 hasLocation W23296030141 @default.
- W2329603014 hasOpenAccess W2329603014 @default.
- W2329603014 hasPrimaryLocation W23296030141 @default.
- W2329603014 hasRelatedWork W1801162136 @default.
- W2329603014 hasRelatedWork W1970940902 @default.
- W2329603014 hasRelatedWork W1971187917 @default.
- W2329603014 hasRelatedWork W1981733502 @default.
- W2329603014 hasRelatedWork W1983965656 @default.
- W2329603014 hasRelatedWork W2003019021 @default.
- W2329603014 hasRelatedWork W2022027801 @default.
- W2329603014 hasRelatedWork W2034701267 @default.
- W2329603014 hasRelatedWork W2052470346 @default.
- W2329603014 hasRelatedWork W2054089903 @default.
- W2329603014 hasRelatedWork W2064135099 @default.
- W2329603014 hasRelatedWork W2087127909 @default.
- W2329603014 hasRelatedWork W2094638481 @default.
- W2329603014 hasRelatedWork W2229724554 @default.
- W2329603014 hasRelatedWork W2320186818 @default.
- W2329603014 hasRelatedWork W2328115058 @default.
- W2329603014 hasRelatedWork W2401178391 @default.
- W2329603014 hasRelatedWork W2412481496 @default.
- W2329603014 hasRelatedWork W2469722706 @default.
- W2329603014 hasRelatedWork W50161146 @default.
- W2329603014 isParatext "false" @default.
- W2329603014 isRetracted "false" @default.
- W2329603014 magId "2329603014" @default.
- W2329603014 workType "article" @default.