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• W2329906403 abstract "The study validated the antidyslipidemic, antioxidant, and antihyperglycemic effects of Lagenaria siceraria fruit extract in human subjects with dyslipidemia along with subjects of normal health. A total of 200 mL of freshly prepared Lagenaria siceraria fruit extract was administered daily on empty stomach for 90 days. Significant reductions ( P < .01) were found in triglycerides and total cholesterol levels in blood. Cardiac risk ratio, atherogenic coefficient, and atherogenicity index of plasma were also improved. Appreciable reductions in body mass index ( P < .01) and blood pressure (systolic P < .01, diastolic P < .05) along with a significant reduction ( P < .05) in fasting blood glucose levels were also observed in these subjects. Lagenaria siceraria fruit extract exhibited significant antioxidant activity in dyslipidemic subjects as evident from elevations in SOD ( P < .05) and GSH levels ( P < .01) with marked improvement in catalase ( P < .01) and TBARS levels ( P < .05). Phytochemical screening confirmed the presence of saponins, glycosides, flavonoids, terpenoids, and phenolic compounds. Lagenaria siceraria fruit extract serves as dietary adjunct in treatment of human dyslipidemia and cardiovascular disease." @default.
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• W2329906403 date "2014-02-20" @default.
• W2329906403 modified "2023-10-12" @default.
• W2329906403 title "Lipid-Lowering and Antioxidant Functions of Bottle Gourd (<i>Lagenaria siceraria</i>) Extract in Human Dyslipidemia" @default.
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• W2329906403 doi "https://doi.org/10.1177/2156587214524229" @default.
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