Matches in SemOpenAlex for { <https://semopenalex.org/work/W2329963727> ?p ?o ?g. }
- W2329963727 endingPage "4134" @default.
- W2329963727 startingPage "4129" @default.
- W2329963727 abstract "Electrical assays potentially offer a highly sensitive, cheap, portable, automated, and multiplexed means of protein biomarker detection, characteristics with an ability to underpin both disease stratification and the development of point of care diagnostics. Most conveniently applied in a reagent free manner, all sensitive assays such as these suffer, however, from profound problems when applied in complex fluids such as blood serum. We report herein, the development, and clinical application, of a highly sensitive and selective electrical insulin biosensor based on a chemisorbed zwittorionic polymer support and a novel reagentless sensing technique based on phase monitoring electrochemical impedance spectroscopy. The polymer adlayer is exceptionally effective in both reducing background response and maintaining receptive antibody binding efficacy, while the non-Faradaic analysis avoids potential interference from background electro-active molecules. Applied to the detection of even a low molecular weight protein (here, insulin), a linear range from 0.1 to 200 pM and an unprecedented femtomolar detection limit are possible in undiluted blood serum." @default.
- W2329963727 created "2016-06-24" @default.
- W2329963727 creator A5046943688 @default.
- W2329963727 creator A5056448190 @default.
- W2329963727 creator A5072178878 @default.
- W2329963727 creator A5085191708 @default.
- W2329963727 creator A5089776239 @default.
- W2329963727 date "2013-03-25" @default.
- W2329963727 modified "2023-10-18" @default.
- W2329963727 title "Ultrasensitive Label Free Electrical Detection of Insulin in Neat Blood Serum" @default.
- W2329963727 cites W1729812787 @default.
- W2329963727 cites W1965067289 @default.
- W2329963727 cites W1970998711 @default.
- W2329963727 cites W1976994545 @default.
- W2329963727 cites W1981118658 @default.
- W2329963727 cites W1983130634 @default.
- W2329963727 cites W2001069796 @default.
- W2329963727 cites W2002337391 @default.
- W2329963727 cites W2009278211 @default.
- W2329963727 cites W2015615857 @default.
- W2329963727 cites W2023067654 @default.
- W2329963727 cites W2023834245 @default.
- W2329963727 cites W2034520377 @default.
- W2329963727 cites W2038342199 @default.
- W2329963727 cites W2039120979 @default.
- W2329963727 cites W2041233437 @default.
- W2329963727 cites W2043772624 @default.
- W2329963727 cites W2051284697 @default.
- W2329963727 cites W2053625635 @default.
- W2329963727 cites W2053957661 @default.
- W2329963727 cites W2056230130 @default.
- W2329963727 cites W2062809899 @default.
- W2329963727 cites W2069661192 @default.
- W2329963727 cites W2078630936 @default.
- W2329963727 cites W2078739630 @default.
- W2329963727 cites W2082378946 @default.
- W2329963727 cites W2089379153 @default.
- W2329963727 cites W2090964222 @default.
- W2329963727 cites W2091762673 @default.
- W2329963727 cites W2095930245 @default.
- W2329963727 cites W2120890726 @default.
- W2329963727 cites W2149411493 @default.
- W2329963727 cites W2172116519 @default.
- W2329963727 cites W2312277926 @default.
- W2329963727 cites W2331738603 @default.
- W2329963727 cites W4210953420 @default.
- W2329963727 cites W4211027657 @default.
- W2329963727 doi "https://doi.org/10.1021/ac4002657" @default.
- W2329963727 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23461715" @default.
- W2329963727 hasPublicationYear "2013" @default.
- W2329963727 type Work @default.
- W2329963727 sameAs 2329963727 @default.
- W2329963727 citedByCount "94" @default.
- W2329963727 countsByYear W23299637272013 @default.
- W2329963727 countsByYear W23299637272014 @default.
- W2329963727 countsByYear W23299637272015 @default.
- W2329963727 countsByYear W23299637272016 @default.
- W2329963727 countsByYear W23299637272017 @default.
- W2329963727 countsByYear W23299637272018 @default.
- W2329963727 countsByYear W23299637272019 @default.
- W2329963727 countsByYear W23299637272020 @default.
- W2329963727 countsByYear W23299637272021 @default.
- W2329963727 countsByYear W23299637272022 @default.
- W2329963727 countsByYear W23299637272023 @default.
- W2329963727 crossrefType "journal-article" @default.
- W2329963727 hasAuthorship W2329963727A5046943688 @default.
- W2329963727 hasAuthorship W2329963727A5056448190 @default.
- W2329963727 hasAuthorship W2329963727A5072178878 @default.
- W2329963727 hasAuthorship W2329963727A5085191708 @default.
- W2329963727 hasAuthorship W2329963727A5089776239 @default.
- W2329963727 hasConcept C10349863 @default.
- W2329963727 hasConcept C119128265 @default.
- W2329963727 hasConcept C160756335 @default.
- W2329963727 hasConcept C171250308 @default.
- W2329963727 hasConcept C178790620 @default.
- W2329963727 hasConcept C185592680 @default.
- W2329963727 hasConcept C192562407 @default.
- W2329963727 hasConcept C40875361 @default.
- W2329963727 hasConcept C43617362 @default.
- W2329963727 hasConcept C55493867 @default.
- W2329963727 hasConceptScore W2329963727C10349863 @default.
- W2329963727 hasConceptScore W2329963727C119128265 @default.
- W2329963727 hasConceptScore W2329963727C160756335 @default.
- W2329963727 hasConceptScore W2329963727C171250308 @default.
- W2329963727 hasConceptScore W2329963727C178790620 @default.
- W2329963727 hasConceptScore W2329963727C185592680 @default.
- W2329963727 hasConceptScore W2329963727C192562407 @default.
- W2329963727 hasConceptScore W2329963727C40875361 @default.
- W2329963727 hasConceptScore W2329963727C43617362 @default.
- W2329963727 hasConceptScore W2329963727C55493867 @default.
- W2329963727 hasIssue "8" @default.
- W2329963727 hasLocation W23299637271 @default.
- W2329963727 hasLocation W23299637272 @default.
- W2329963727 hasOpenAccess W2329963727 @default.
- W2329963727 hasPrimaryLocation W23299637271 @default.
- W2329963727 hasRelatedWork W2063401993 @default.
- W2329963727 hasRelatedWork W2087074083 @default.
- W2329963727 hasRelatedWork W2094687687 @default.