FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2330037276> ?p ?o ?g. }

• W2330037276 abstract "Cardiovascular disease (CVD) is leading cause of premature death worldwide. 30% of all global deaths in 2005, i.e. 17.5 million people died from this CVD. If proper and quick actions are not taken, an estimated number of 20 million people will die by 2015, including stroke [1]. Lavie et al. [2] stated regarding fiscal burden of CVD and, especially, coronary heart disease (CHD), most medical treatments are directed at the major CHD risk factors. CVD implies to any medical disorders related to heart and blood vessels. There are a number of known causative factors that are directly or indirectly responsible for CVD. The lipid triad refers basically to three lipid abnormalities: increased plasma triglycerides and small dense low density lipoprotein (sd-LDL), and decreased high density lipoprotein cholesterol (HDL-C) concentrations. Since lipid triad is highly atherogenic in nature causing CVD, also called as atherogenic lipoprotein phenotype. The liver secretes lipoproteins called very-low-density lipoproteins (VLDL) rich in triglycerides. As these lipoproteins come into contact with lipoprotein lipase situated on capillary endothelial cell, hydrolyzes the triglycerides leaving VLDL remnant. Many patients with premature CHD having cholesterol levels in the range of 200-240 mg/dl show other risk factors like hypertension, obesity or abnormalities in triglycerides metabolism. But these above anomalies are often seen in reduced concentration of HDL [3]. Low density lipoprotein cholesterol (LDL-C) rich in cholesterol has been extensively studied and known for its bad cholesterol because it is considered as a good marker for cardiovascular disease risk assessment [4] and its level in human body should be below 130 mg/dl. HDL-C ranging between 35-40 mg/dl is considered as good cholesterol as it helps in the removal of cholesterol along with it also shows antioxidant property carrying arylesterase/ paraoxonase antioxidant enzyme. High level about 60 mg/dl of HDL-C is believed to be played a good protective role in human health protection as it protects efficiently heart from dangerous attack on it. The various previous studies clearly indicate that high concentration of LDL-C and substantially increased ratio of LDL and HDL are important risk factors which promote atherosclerosis [5]. The study for UK Progression of Diabetes Study showed that LDL-C is the strongest risk factor for coronary heart disease followed by HDL-C in this population [6]. Thus it suggested that 0.1 mM rise in HDL-C would decrease coronary heart disease by 15%. LDL particles are differentiated into large buoyant LDL (lb-LDL) and small dense LDL (sd-LDL). These subfractions are associated with difference in size, density, physico-chemical composition, metabolic behavior and atherogenicity. Different known techniques such as density gradient, ultracentrifugation, polyacrylamide gel electrophoresis, nuclear magnetic resonance, etc. are employed for fractionation of LDL into sd-LDL and lb-LDL subfractions [7-9]. Lb-LDL particle shows >25.5 nm while sd-LDL particle shows ≤ 25.5 nm." @default.
• W2330037276 created "2016-06-24" @default.
• W2330037276 creator A5001374735 @default.
• W2330037276 creator A5046139094 @default.
• W2330037276 creator A5048087803 @default.
• W2330037276 date "2013-01-01" @default.
• W2330037276 modified "2023-10-05" @default.
• W2330037276 title "Lipid Triad: An Important Predictor of Dyslipidemia Related Disorders and its Therapeutic Intervention" @default.
• W2330037276 cites W131540432 @default.
• W2330037276 cites W1511956154 @default.
• W2330037276 cites W1969525279 @default.
• W2330037276 cites W1976518583 @default.
• W2330037276 cites W1985992779 @default.
• W2330037276 cites W200092697 @default.
• W2330037276 cites W2003956286 @default.
• W2330037276 cites W2013856702 @default.
• W2330037276 cites W2045773814 @default.
• W2330037276 cites W2053365438 @default.
• W2330037276 cites W2053802334 @default.
• W2330037276 cites W2057132562 @default.
• W2330037276 cites W2088383768 @default.
• W2330037276 cites W2107818754 @default.
• W2330037276 cites W2116927692 @default.
• W2330037276 cites W2117492262 @default.
• W2330037276 cites W2118310760 @default.
• W2330037276 cites W2130835505 @default.
• W2330037276 cites W2146244882 @default.
• W2330037276 cites W2154477895 @default.
• W2330037276 cites W2323594275 @default.
• W2330037276 cites W2328198901 @default.
• W2330037276 cites W2337109902 @default.
• W2330037276 doi "https://doi.org/10.4172/2153-0637.1000e114" @default.
• W2330037276 hasPublicationYear "2013" @default.
• W2330037276 type Work @default.
• W2330037276 sameAs 2330037276 @default.
• W2330037276 citedByCount "2" @default.
• W2330037276 countsByYear W23300372762020 @default.
• W2330037276 countsByYear W23300372762021 @default.
• W2330037276 crossrefType "journal-article" @default.
• W2330037276 hasAuthorship W2330037276A5001374735 @default.
• W2330037276 hasAuthorship W2330037276A5046139094 @default.
• W2330037276 hasAuthorship W2330037276A5048087803 @default.
• W2330037276 hasConcept C11171543 @default.
• W2330037276 hasConcept C118552586 @default.
• W2330037276 hasConcept C134018914 @default.
• W2330037276 hasConcept C15744967 @default.
• W2330037276 hasConcept C176038584 @default.
• W2330037276 hasConcept C2778096610 @default.
• W2330037276 hasConcept C2780665704 @default.
• W2330037276 hasConcept C555293320 @default.
• W2330037276 hasConcept C60644358 @default.
• W2330037276 hasConcept C70721500 @default.
• W2330037276 hasConcept C71924100 @default.
• W2330037276 hasConcept C86803240 @default.
• W2330037276 hasConceptScore W2330037276C11171543 @default.
• W2330037276 hasConceptScore W2330037276C118552586 @default.
• W2330037276 hasConceptScore W2330037276C134018914 @default.
• W2330037276 hasConceptScore W2330037276C15744967 @default.
• W2330037276 hasConceptScore W2330037276C176038584 @default.
• W2330037276 hasConceptScore W2330037276C2778096610 @default.
• W2330037276 hasConceptScore W2330037276C2780665704 @default.
• W2330037276 hasConceptScore W2330037276C555293320 @default.
• W2330037276 hasConceptScore W2330037276C60644358 @default.
• W2330037276 hasConceptScore W2330037276C70721500 @default.
• W2330037276 hasConceptScore W2330037276C71924100 @default.
• W2330037276 hasConceptScore W2330037276C86803240 @default.
• W2330037276 hasIssue "01" @default.
• W2330037276 hasLocation W23300372761 @default.
• W2330037276 hasOpenAccess W2330037276 @default.
• W2330037276 hasPrimaryLocation W23300372761 @default.
• W2330037276 hasRelatedWork W2010373913 @default.
• W2330037276 hasRelatedWork W2082415271 @default.
• W2330037276 hasRelatedWork W2318807671 @default.
• W2330037276 hasRelatedWork W2330037276 @default.
• W2330037276 hasRelatedWork W2557117804 @default.
• W2330037276 hasRelatedWork W3164661289 @default.
• W2330037276 hasRelatedWork W3196250570 @default.
• W2330037276 hasRelatedWork W4213370102 @default.
• W2330037276 hasRelatedWork W4290565217 @default.
• W2330037276 hasRelatedWork W4385968503 @default.
• W2330037276 hasVolume "03" @default.
• W2330037276 isParatext "false" @default.
• W2330037276 isRetracted "false" @default.
• W2330037276 magId "2330037276" @default.
• W2330037276 workType "article" @default.