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• W2330112978 abstract "Severe respiratory failure in newborn and pediatric patients is associated with significant morbidity and mortality. Basic science laboratory investigation has led to advances both in our understanding of ventilator-induced lung injury and in optimizing the supportive use of conventional ventilation strategies. Over the past few years, progress has been made in alternative therapies for ventilating both children and adults with severe respiratory failure. This review focuses on recent laboratory and clinical data detailing the techniques of permissive hypercapnia, high frequency oscillatory ventilation, inhaled nitric oxide, intratracheal pulmonary ventilation, and liquid ventilation. Some of these modalities are becoming commonplace, and others may have much to offer the clinician if their benefit is clearly demonstrated in future clinical trials. Curr Opin Pediatr 11:241 −248 © 1999 Lippincott Williams & Williams, Inc." @default.
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• W2330112978 date "1999-06-01" @default.
• W2330112978 modified "2023-10-14" @default.
• W2330112978 title "Advances in ventilatory support of the pediatric surgical patient" @default.
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• W2330112978 doi "https://doi.org/10.1097/00008480-199906000-00013" @default.
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