Matches in SemOpenAlex for { <https://semopenalex.org/work/W2330123487> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W2330123487 endingPage "781" @default.
- W2330123487 startingPage "775" @default.
- W2330123487 abstract "Rats were given a powder diet containing dibutyl phthalate (DBP), monobutyl phthalate (MBP), di-2-ethylhexyl phthalate (DEHP) or phthalic acid (PA) at a level of 0.5 or 5% for 34 to 36 days, respectively. The rats treated with a 5% diet of DBP, MBP or DEHP revealed growth depression, liver enlargement, testicular atrophy, decreased activities of succinate and pyruvate dehydrogenases in liver mitochondria, and abnormal changes in biochemical tests of serum and in histological examinations of the liver and testicle. These adverse effects were also observed in rats fed a 0.5% diet of these compounds, although they were less severe. On the other hand, PA had no effect, even at a 5% concentration in the diet.The changes in hepatocellular ultrastructure were more prominent in rats treated with DBP than in those given MBP. The most striking difference between DBP and MBP was that DBP showed a potent inhibitory effect on succinate dehydrogenase activity in liver mitochondria in vitro, wherease MBP showed no such effect. This difference was also observed in liver mitochondrial respiration in vitro.It was suggested that the adverse effects of orally administered DBP at least on the liver may be caused partly by the direct action of intact DBP entering the liver." @default.
- W2330123487 created "2016-06-24" @default.
- W2330123487 creator A5002367052 @default.
- W2330123487 creator A5035783236 @default.
- W2330123487 creator A5074817231 @default.
- W2330123487 date "1986-01-01" @default.
- W2330123487 modified "2023-09-27" @default.
- W2330123487 title "Toxicity of dibutyl phthalate and its metabolites in rats." @default.
- W2330123487 cites W1597711166 @default.
- W2330123487 cites W1757365663 @default.
- W2330123487 cites W1984002265 @default.
- W2330123487 cites W1994560715 @default.
- W2330123487 cites W2007352391 @default.
- W2330123487 cites W2013951537 @default.
- W2330123487 cites W2021657137 @default.
- W2330123487 cites W2034109514 @default.
- W2330123487 cites W2040393890 @default.
- W2330123487 cites W2060681200 @default.
- W2330123487 cites W2062718001 @default.
- W2330123487 cites W2079594367 @default.
- W2330123487 cites W2333186643 @default.
- W2330123487 cites W2408128128 @default.
- W2330123487 doi "https://doi.org/10.1265/jjh.41.775" @default.
- W2330123487 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3807024" @default.
- W2330123487 hasPublicationYear "1986" @default.
- W2330123487 type Work @default.
- W2330123487 sameAs 2330123487 @default.
- W2330123487 citedByCount "7" @default.
- W2330123487 countsByYear W23301234872014 @default.
- W2330123487 crossrefType "journal-article" @default.
- W2330123487 hasAuthorship W2330123487A5002367052 @default.
- W2330123487 hasAuthorship W2330123487A5035783236 @default.
- W2330123487 hasAuthorship W2330123487A5074817231 @default.
- W2330123487 hasBestOaLocation W23301234871 @default.
- W2330123487 hasConcept C126322002 @default.
- W2330123487 hasConcept C134018914 @default.
- W2330123487 hasConcept C178790620 @default.
- W2330123487 hasConcept C185592680 @default.
- W2330123487 hasConcept C202751555 @default.
- W2330123487 hasConcept C2777414220 @default.
- W2330123487 hasConcept C2777892665 @default.
- W2330123487 hasConcept C2779643248 @default.
- W2330123487 hasConcept C2781005124 @default.
- W2330123487 hasConcept C2781172350 @default.
- W2330123487 hasConcept C28859421 @default.
- W2330123487 hasConcept C29730261 @default.
- W2330123487 hasConcept C2993709057 @default.
- W2330123487 hasConcept C55493867 @default.
- W2330123487 hasConcept C71924100 @default.
- W2330123487 hasConcept C86803240 @default.
- W2330123487 hasConceptScore W2330123487C126322002 @default.
- W2330123487 hasConceptScore W2330123487C134018914 @default.
- W2330123487 hasConceptScore W2330123487C178790620 @default.
- W2330123487 hasConceptScore W2330123487C185592680 @default.
- W2330123487 hasConceptScore W2330123487C202751555 @default.
- W2330123487 hasConceptScore W2330123487C2777414220 @default.
- W2330123487 hasConceptScore W2330123487C2777892665 @default.
- W2330123487 hasConceptScore W2330123487C2779643248 @default.
- W2330123487 hasConceptScore W2330123487C2781005124 @default.
- W2330123487 hasConceptScore W2330123487C2781172350 @default.
- W2330123487 hasConceptScore W2330123487C28859421 @default.
- W2330123487 hasConceptScore W2330123487C29730261 @default.
- W2330123487 hasConceptScore W2330123487C2993709057 @default.
- W2330123487 hasConceptScore W2330123487C55493867 @default.
- W2330123487 hasConceptScore W2330123487C71924100 @default.
- W2330123487 hasConceptScore W2330123487C86803240 @default.
- W2330123487 hasIssue "4" @default.
- W2330123487 hasLocation W23301234871 @default.
- W2330123487 hasLocation W23301234872 @default.
- W2330123487 hasOpenAccess W2330123487 @default.
- W2330123487 hasPrimaryLocation W23301234871 @default.
- W2330123487 hasRelatedWork W1999014743 @default.
- W2330123487 hasRelatedWork W2006261800 @default.
- W2330123487 hasRelatedWork W2044477941 @default.
- W2330123487 hasRelatedWork W2053594689 @default.
- W2330123487 hasRelatedWork W2066878189 @default.
- W2330123487 hasRelatedWork W2328062175 @default.
- W2330123487 hasRelatedWork W2330123487 @default.
- W2330123487 hasRelatedWork W2355980937 @default.
- W2330123487 hasRelatedWork W2369670619 @default.
- W2330123487 hasRelatedWork W2369892356 @default.
- W2330123487 hasVolume "41" @default.
- W2330123487 isParatext "false" @default.
- W2330123487 isRetracted "false" @default.
- W2330123487 magId "2330123487" @default.
- W2330123487 workType "article" @default.