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- W2330330117 abstract "More than 28 years have passed since Al-Hasani et al1Al-Hasani M.K. Saltissi D. Chang R. Van Goor H. Tegzess A.M. Successful regrafting of an explanted transplant kidney.Transplantation. 1987; 43: 916-917Crossref PubMed Google Scholar first reported on the reuse of a kidney allograft. However, there are still few long-term follow-up data regarding such reuse.2Goralczyk A.D. Obed A. Lorf T. Fourteen-year survival of a renal graft reused 2 years after initial transplantation: a case report.Transpl Int. 2010; 23: 15-17Crossref Scopus (7) Google Scholar, 3Kadambi P.V. Chon W.J. Josephson M.A. et al.Reuse of a previously transplanted kidney: does success come with a price?.Clin Kidney J. 2012; 5: 434-437Crossref PubMed Scopus (12) Google Scholar, 4Lugo-Baruqui J. Burke G.W. Guerra G. Ruiz P. Ciancio G. Ten-year follow-up of a reused kidney graft for transplant using sirolimus for maintenance ımmunosuppression.Transplant Proc. 2015; 47: 3027-3030Abstract Full Text Full Text PDF PubMed Scopus (3) Google Scholar In July 2007, we reported in AJKD a case of successful kidney allograft reuse from a deceased kidney transplant recipient.5Celik A. Saglam F. Cavdar C. et al.Successful reuse of a transplanted kidney: 3-year follow-up.Am J Kidney Dis. 2007; 50: 143-145Abstract Full Text Full Text PDF PubMed Scopus (14) Google Scholar The first recipient of the transplanted kidney survived 6 years with good kidney function, but in April 2003 experienced an intracranial hemorrhage and was pronounced brain dead in our hospital. A 24-year-old man who had been treated with maintenance hemodialysis for 3 years became the second recipient of the allograft. At the time of writing, 12 years after transplantation, the second recipient has a serum creatinine level of 1.3 mg/dL (corresponding to an estimated glomerular filtration rate of 61 mL/min/1.73 m2 as calculated by the MDRD [Modification of Diet in Renal Disease] Study equation). Protein and blood are not detectable by standard urinalysis, and 24-hour urine protein excretion is 100 mg/d. The patient’s blood pressure is 130/80 mm Hg with treatment with valsartan and carvedilol. His current immunosuppressive regimen includes prednisolone (5 mg/d), azathioprine (50 mg/d), and tacrolimus (1.5 mg/d). We believe that our experience—reuse of a kidney allograft 6 years after the initial transplantation and with excellent allograft function 12 years postretransplantation—shows that previously used allografts are a potential source of kidneys for transplantation when donor-recipient pairs are carefully selected and the immunosuppression protocol is tailored to the original allograft. Support: None. Financial Disclosure: The authors declare that they have no relevant interests. Peer Review: Evaluated by a Co-Editor and the Editor-in-Chief. Successful Reuse of a Transplanted Kidney: 3-Year Follow-UpAmerican Journal of Kidney DiseasesVol. 50Issue 1PreviewThe number of new transplantations has not kept pace with the ever-growing number of patients waiting for a kidney transplant, and there has been a growing shortage of deceased donor kidneys. Previously transplanted organs have been used to increase the donor pool. There is very little data about the reuse of a transplanted kidney. We report a case of successful reuse of a kidney graft after the death of the first recipient with a 3-year follow-up. Full-Text PDF" @default.
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- W2330330117 date "2016-06-01" @default.
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- W2330330117 title "Long-term Follow-up of a Reused Kidney Allograft" @default.
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- W2330330117 doi "https://doi.org/10.1053/j.ajkd.2016.02.047" @default.
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