Matches in SemOpenAlex for { <https://semopenalex.org/work/W2330393472> ?p ?o ?g. }
- W2330393472 endingPage "147032031662871" @default.
- W2330393472 startingPage "147032031662871" @default.
- W2330393472 abstract "Currently, there is no effective therapy available for liver fibrosis. This study aims to evaluate the efficacy of renin angiotensin system inhibitors on liver fibrosis.Full-text randomized controlled trials in patients with liver fibrosis were identified and included in the meta-analysis. The primary outcome measure was the histological fibrosis score of the liver. Secondary outcome measures included fibrosis area of the liver, serological levels of fibrosis markers, adverse events, and withdrawals.From 6973 non-duplicated entries by systematic search, four randomized controlled trials with 210 patients were identified. The renin angiotensin system inhibitors therapy resulted in a marginally significant reduction in liver fibrosis score (MD = -0.30; 95% CI: -0.62-0.02, p = 0.05) and a significant reduction in liver fibrosis area (MD = -2.36%; 95% CI: -4.22%--0.50%, p = 0.01) as compared with control. The therapy was well tolerated and there was no significant difference in withdrawals between treatment and control groups (RD = 0.00; 95% CI: -0.06-0.06, p = 0.97).Renin angiotensin system inhibitor therapy results in a reduction in liver fibrosis score and liver fibrosis area in patients with hepatic fibrosis with good safety profile. However, randomized controlled trials of high-quality will clarify the effectiveness of renin angiotensin system inhibitors on liver fibrosis." @default.
- W2330393472 created "2016-06-24" @default.
- W2330393472 creator A5019186596 @default.
- W2330393472 creator A5031315906 @default.
- W2330393472 creator A5038611998 @default.
- W2330393472 creator A5044138805 @default.
- W2330393472 creator A5045771501 @default.
- W2330393472 creator A5046521928 @default.
- W2330393472 creator A5057717552 @default.
- W2330393472 creator A5061364009 @default.
- W2330393472 date "2016-02-27" @default.
- W2330393472 modified "2023-10-01" @default.
- W2330393472 title "Therapeutic effect of renin angiotensin system inhibitors on liver fibrosis" @default.
- W2330393472 cites W1480729244 @default.
- W2330393472 cites W1528031070 @default.
- W2330393472 cites W1942321192 @default.
- W2330393472 cites W1963879129 @default.
- W2330393472 cites W1967059750 @default.
- W2330393472 cites W1967665543 @default.
- W2330393472 cites W1970588973 @default.
- W2330393472 cites W1971467647 @default.
- W2330393472 cites W1979287099 @default.
- W2330393472 cites W1980437893 @default.
- W2330393472 cites W1984611853 @default.
- W2330393472 cites W1984870942 @default.
- W2330393472 cites W1986215651 @default.
- W2330393472 cites W1990696850 @default.
- W2330393472 cites W1990781015 @default.
- W2330393472 cites W1991863368 @default.
- W2330393472 cites W1994559017 @default.
- W2330393472 cites W1994733930 @default.
- W2330393472 cites W2000649393 @default.
- W2330393472 cites W2004972926 @default.
- W2330393472 cites W2005922664 @default.
- W2330393472 cites W2009746223 @default.
- W2330393472 cites W2011932878 @default.
- W2330393472 cites W2013926077 @default.
- W2330393472 cites W2019604389 @default.
- W2330393472 cites W2027814849 @default.
- W2330393472 cites W2030739359 @default.
- W2330393472 cites W2034667224 @default.
- W2330393472 cites W2036321154 @default.
- W2330393472 cites W2037332127 @default.
- W2330393472 cites W2038693293 @default.
- W2330393472 cites W2043070445 @default.
- W2330393472 cites W2044710035 @default.
- W2330393472 cites W2051719637 @default.
- W2330393472 cites W2052045228 @default.
- W2330393472 cites W2052926532 @default.
- W2330393472 cites W2054793162 @default.
- W2330393472 cites W2058787613 @default.
- W2330393472 cites W2059307783 @default.
- W2330393472 cites W2061103878 @default.
- W2330393472 cites W2062823155 @default.
- W2330393472 cites W2073628059 @default.
- W2330393472 cites W2110243916 @default.
- W2330393472 cites W2110337697 @default.
- W2330393472 cites W2122811145 @default.
- W2330393472 cites W2126930838 @default.
- W2330393472 cites W2127341163 @default.
- W2330393472 cites W2129736259 @default.
- W2330393472 cites W2134338262 @default.
- W2330393472 cites W2136578956 @default.
- W2330393472 cites W2147515973 @default.
- W2330393472 cites W2148420637 @default.
- W2330393472 cites W2149346967 @default.
- W2330393472 cites W2157263411 @default.
- W2330393472 cites W2159686760 @default.
- W2330393472 cites W2160887608 @default.
- W2330393472 cites W2241455767 @default.
- W2330393472 cites W2313367923 @default.
- W2330393472 cites W2360995357 @default.
- W2330393472 cites W2389463740 @default.
- W2330393472 cites W239124720 @default.
- W2330393472 cites W2460144942 @default.
- W2330393472 cites W265891971 @default.
- W2330393472 cites W2774287907 @default.
- W2330393472 cites W34619435 @default.
- W2330393472 cites W4214559180 @default.
- W2330393472 cites W4254398554 @default.
- W2330393472 cites W4255712601 @default.
- W2330393472 doi "https://doi.org/10.1177/1470320316628717" @default.
- W2330393472 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5843853" @default.
- W2330393472 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27009285" @default.
- W2330393472 hasPublicationYear "2016" @default.
- W2330393472 type Work @default.
- W2330393472 sameAs 2330393472 @default.
- W2330393472 citedByCount "33" @default.
- W2330393472 countsByYear W23303934722017 @default.
- W2330393472 countsByYear W23303934722018 @default.
- W2330393472 countsByYear W23303934722019 @default.
- W2330393472 countsByYear W23303934722020 @default.
- W2330393472 countsByYear W23303934722021 @default.
- W2330393472 countsByYear W23303934722022 @default.
- W2330393472 countsByYear W23303934722023 @default.
- W2330393472 crossrefType "journal-article" @default.
- W2330393472 hasAuthorship W2330393472A5019186596 @default.
- W2330393472 hasAuthorship W2330393472A5031315906 @default.