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- W2330432969 abstract "BIZARRE morphologic abnormalities of the erythrocytes are generally not considered a prominent feature of congenital nonspherocytic hemolytic anemias.1 , 2 We have observed a child with a severe congenital nonspherocytic hemolytic anemia associated with a deficiency of erythrocyte pyruvate kinase in whom morphologic abnormalities of the red cells were profound. The bizarre red-cell abnormality was in some respects similar to that observed in the syndrome of acanthocytosis associated with absence of serum beta-lipoprotein.3 Of additional interest was the finding that the mother of the patient was not only a heterozygote for the pyruvate kinase (PK) deficiency but was also a carrier of . . ." @default.
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- W2330432969 date "1964-05-14" @default.
- W2330432969 modified "2023-09-24" @default.
- W2330432969 title "Extreme Hemolysis and Red-Cell Distortion in Erythrocyte Pyruvate Kinase Deficiency" @default.
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- W2330432969 doi "https://doi.org/10.1056/nejm196405142702001" @default.
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