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• W2330491330 endingPage "86" @default.
• W2330491330 startingPage "78" @default.
• W2330491330 abstract "This study aims to demonstrate the morphology and in vitro biocompatibility of neat and surface-modified hydroxyapatite sponge scaffold (SM-HASS) which was fabricated using a sponge replica method, and compared with the commercially available demineralized freeze-dried bone allograft (DFDBA). Surface-modifications were done by coating the surface area of the neat hydroxyapatite sponge scaffold (HASS) with either gelatin alone (HASS/G) or gelatin and BMP-2 growth factor (HASS/G+B). Scanning electron microscope (SEM), Fourier transform infrared (FTIR), porosity, pore size distribution, and compressive strength analyses showed that the addition of gelatin in HASS/G produced a morphologically and structurally similar scaffold to that of the allograft. The addition of BMP-2 improved the biocompatibility of the HASS/G+B in vitro using MC3T3-E1 cells which showed better cell viability, proliferation, and cell adhesion than on the allograft. Therefore, hydroxyapatite scaffold coated with gelatin polymer and gelatin with BMP-2 growth factor showed comparable performance against commercially available DFDBA from cadaver with regards to structure and in vitro biocompatibility." @default.
• W2330491330 created "2016-06-24" @default.
• W2330491330 creator A5068217095 @default.
• W2330491330 creator A5089050029 @default.
• W2330491330 creator A5090528786 @default.
• W2330491330 date "2015-01-01" @default.
• W2330491330 modified "2023-09-26" @default.
• W2330491330 title "Improved In Vitro Biocompatibility of Surface-Modified Hydroxyapatite Sponge Scaffold with Gelatin and BMP-2 in Comparison Against a Commercial Bone Allograft" @default.
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• W2330491330 doi "https://doi.org/10.1097/mat.0000000000000155" @default.
• W2330491330 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25248041" @default.
• W2330491330 hasPublicationYear "2015" @default.
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