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• W2330573684 abstract "The response of submandibular salivary secretion in rats of several age groups was examined with the administrations of α and β-adrenergic agonists.Submandibular saliva was collected intraorally from male Sprague-Dawley strain rats of 2 to 8 weeks of age as immature, and 12-15 weeks of age as mature. Noradrenaline (2mg/kg) or phenylephrine (6mg/kg) as α-adrenergic agonists, and isoproterenol (30mg/kg) as β-adrenergic agonist were administered i. p. for collecting saliva.Results obtained were as follows: The response of salivary secretion, such as salivary volumes, flow rate and protein concentration, in the rats of 7-8 weeks did not significantry differ from that of mature rats. In the response to β-adrenergic agonist by disc electrophoresis, types of secreted proteins in 6-week rats resembled that in mature rats. In the response to a-adrenergic agonists by disc electrophoresis, types of secreted proteins in 7-week rats resembled that in mature rats. However, types of secreted proteins in the rats of 2 to 5 weeks of age were similar to the case of β-adrenergic agonist. The result of analysis of isoelectric focusing indicated that secreted proteins by α-adrenergic agonist in 7-week rats resembled those in mature rats. By chronic noradrenaline (1mg/kg) administration, the growth rates of body weights and submandibular wet weights in 4-week rats were slightly suppressed as compared with those in the control rats." @default.
• W2330573684 created "2016-06-24" @default.
• W2330573684 creator A5083901411 @default.
• W2330573684 date "1981-01-01" @default.
• W2330573684 modified "2023-09-24" @default.
• W2330573684 title "Studies on the difference of salivary response to catecholamines in developing rat submandibular gland" @default.
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• W2330573684 doi "https://doi.org/10.2330/joralbiosci1965.23.335" @default.
• W2330573684 hasPublicationYear "1981" @default.
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