Matches in SemOpenAlex for { <https://semopenalex.org/work/W2330607668> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W2330607668 endingPage "851" @default.
- W2330607668 startingPage "845" @default.
- W2330607668 abstract "The objective of the present study was to investigate whether early undernutrition changes the chronic inflammatory response, so as to study its influence on pharmacological response to indomethacin. Rat offspring of dams fed from the first day of gestation to term or throughout the lactation period received a balanced diet (NN) or a basic regional diet (BRD) from northeast Brazil. According to their dams, the offspring were divided into three groups: NN; basic regional diet during gestation (BRD-g, undernourished during gestation); basic regional diet during gestation and lactation (BRD-gl, undernourished during gestation and lactation). At 2 months of age, Freund's adjuvant (0·2 ml) was inoculated into the plantar surface of the hind paw (day 0) of animals. All animals orally received saline (0·9 %) for 28 d. Another group of adult offspring was subjected to the same procedure as described above, but orally received indomethacin (2 mg/kg) instead of saline, and divided into three subgroups: NN treated with indomethacin (NNI); BRD-g treated with indomethacin (BRDI-g); BRD-gl treated with indomethacin (BRDI-gl). The hind paw volume was calculated on days 0 (initial paw volume), 7, 14 and 28. Hind paw swelling, blood albumin and C-reactive protein (CRP) levels and leucocyte counts were evaluated as markers of inflammation. Reduced hind paw swelling and the blood levels of serum albumin and CRP were found in the BRD-g and BRD-gl offspring. However, no difference was found in the leucocyte count. Compared with their respective saline-treated groups (NN, BRD-g and BRD-gl), the anti-inflammatory effect of indomethacin was lower in the BRDI-g and BRDI-gl groups than in the NNI group. We conclude that early undernutrition attenuated the chronic inflammatory response and the anti-inflammatory effect of indomethacin." @default.
- W2330607668 created "2016-06-24" @default.
- W2330607668 creator A5046238443 @default.
- W2330607668 creator A5056068944 @default.
- W2330607668 creator A5061994628 @default.
- W2330607668 creator A5068462320 @default.
- W2330607668 creator A5073740097 @default.
- W2330607668 creator A5078978956 @default.
- W2330607668 date "2011-05-09" @default.
- W2330607668 modified "2023-10-18" @default.
- W2330607668 title "Impact of early malnourishment on the chronic inflammatory response and its implications for the effect of indomethacin on Wistar rats" @default.
- W2330607668 cites W1971581697 @default.
- W2330607668 cites W1988168615 @default.
- W2330607668 cites W1990759351 @default.
- W2330607668 cites W1996956490 @default.
- W2330607668 cites W2004947549 @default.
- W2330607668 cites W2011151958 @default.
- W2330607668 cites W2041823432 @default.
- W2330607668 cites W2051420874 @default.
- W2330607668 cites W2057325985 @default.
- W2330607668 cites W2058770010 @default.
- W2330607668 cites W2059041633 @default.
- W2330607668 cites W2068949553 @default.
- W2330607668 cites W2102973745 @default.
- W2330607668 cites W2107494503 @default.
- W2330607668 cites W2126546435 @default.
- W2330607668 cites W2131165622 @default.
- W2330607668 cites W2134836294 @default.
- W2330607668 cites W2145253917 @default.
- W2330607668 cites W2149939912 @default.
- W2330607668 doi "https://doi.org/10.1017/s0007114511001127" @default.
- W2330607668 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21736850" @default.
- W2330607668 hasPublicationYear "2011" @default.
- W2330607668 type Work @default.
- W2330607668 sameAs 2330607668 @default.
- W2330607668 citedByCount "6" @default.
- W2330607668 countsByYear W23306076682012 @default.
- W2330607668 countsByYear W23306076682014 @default.
- W2330607668 countsByYear W23306076682015 @default.
- W2330607668 countsByYear W23306076682019 @default.
- W2330607668 countsByYear W23306076682021 @default.
- W2330607668 crossrefType "journal-article" @default.
- W2330607668 hasAuthorship W2330607668A5046238443 @default.
- W2330607668 hasAuthorship W2330607668A5056068944 @default.
- W2330607668 hasAuthorship W2330607668A5061994628 @default.
- W2330607668 hasAuthorship W2330607668A5068462320 @default.
- W2330607668 hasAuthorship W2330607668A5073740097 @default.
- W2330607668 hasAuthorship W2330607668A5078978956 @default.
- W2330607668 hasBestOaLocation W23306076681 @default.
- W2330607668 hasConcept C112672928 @default.
- W2330607668 hasConcept C126322002 @default.
- W2330607668 hasConcept C134018914 @default.
- W2330607668 hasConcept C2776125364 @default.
- W2330607668 hasConcept C2776659692 @default.
- W2330607668 hasConcept C2777397205 @default.
- W2330607668 hasConcept C2779234561 @default.
- W2330607668 hasConcept C46973012 @default.
- W2330607668 hasConcept C51738704 @default.
- W2330607668 hasConcept C54355233 @default.
- W2330607668 hasConcept C71924100 @default.
- W2330607668 hasConcept C86803240 @default.
- W2330607668 hasConceptScore W2330607668C112672928 @default.
- W2330607668 hasConceptScore W2330607668C126322002 @default.
- W2330607668 hasConceptScore W2330607668C134018914 @default.
- W2330607668 hasConceptScore W2330607668C2776125364 @default.
- W2330607668 hasConceptScore W2330607668C2776659692 @default.
- W2330607668 hasConceptScore W2330607668C2777397205 @default.
- W2330607668 hasConceptScore W2330607668C2779234561 @default.
- W2330607668 hasConceptScore W2330607668C46973012 @default.
- W2330607668 hasConceptScore W2330607668C51738704 @default.
- W2330607668 hasConceptScore W2330607668C54355233 @default.
- W2330607668 hasConceptScore W2330607668C71924100 @default.
- W2330607668 hasConceptScore W2330607668C86803240 @default.
- W2330607668 hasIssue "6" @default.
- W2330607668 hasLocation W23306076681 @default.
- W2330607668 hasLocation W23306076682 @default.
- W2330607668 hasOpenAccess W2330607668 @default.
- W2330607668 hasPrimaryLocation W23306076681 @default.
- W2330607668 hasRelatedWork W1502579087 @default.
- W2330607668 hasRelatedWork W1591616590 @default.
- W2330607668 hasRelatedWork W2009428258 @default.
- W2330607668 hasRelatedWork W2010225050 @default.
- W2330607668 hasRelatedWork W2036659686 @default.
- W2330607668 hasRelatedWork W2064652474 @default.
- W2330607668 hasRelatedWork W2110681150 @default.
- W2330607668 hasRelatedWork W2500314183 @default.
- W2330607668 hasRelatedWork W3160140598 @default.
- W2330607668 hasRelatedWork W4239714589 @default.
- W2330607668 hasVolume "106" @default.
- W2330607668 isParatext "false" @default.
- W2330607668 isRetracted "false" @default.
- W2330607668 magId "2330607668" @default.
- W2330607668 workType "article" @default.