FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2330794800> ?p ?o ?g. }

• W2330794800 endingPage "6764" @default.
• W2330794800 startingPage "6756" @default.
• W2330794800 abstract "Purpose.: Macular pucker (MP) and macular hole (MH) are vitreomaculopathies treated by vitrectomy and membrane peel. The complication of postoperative central scotoma can be associated with significant reduction in visual acuity (VA). We seek to determine whether retinal nerve fiber layer (RNFL) disruption is the pathophysiologic basis of this defect. Mitigating clinical circumstances also were sought. Methods.: Eleven eyes from 10 pseudophakic patients who had undergone vitrectomy with peeling for either MH or MP were studied with clinical measures, including optical coherence tomography (OCT). Membrane specimens were evaluated by immunohistochemistry for neurofilament, a marker for the inner retina. Ten eyes from 10 pseudophakic patients who underwent repeat surgery for persistent or recurrent pathology were evaluated to determine the relationship between the timing of reoperation and clinical outcome. Results.: Cases with a postoperative central scotoma (N = 4) had worse VA (~20/600) compared to those without (N = 7, ~20/30, P = 0.01). Eyes with a central scotoma had significantly reduced RNFL thickness in the temporal quadrant (53.67 vs. 72.33 μm, P = 0.05) by OCT. A central scotoma was associated with more disruption of the inner retina on immunohistochemistry (P = 0.03). In patients with persistent or recurrent pathology, waiting six months before reoperation resulted in better functional outcomes (P = 0.03). Conclusions.: Central scotomata and poor VA were associated with disruption of the RNFL during membrane peeling. Affected patients have RNFL thinning and signs of optic neuropathy, for which we propose the term inner retinal optic neuropathy (IRON). In patients requiring reoperation, waiting six months between surgeries may reduce the risk of IRON." @default.
• W2330794800 created "2016-06-24" @default.
• W2330794800 creator A5013092199 @default.
• W2330794800 creator A5037098482 @default.
• W2330794800 creator A5065390232 @default.
• W2330794800 creator A5065452265 @default.
• W2330794800 creator A5080146086 @default.
• W2330794800 date "2014-09-18" @default.
• W2330794800 modified "2023-10-16" @default.
• W2330794800 title "Inner Retinal Optic Neuropathy: Vitreomacular Surgery-Associated Disruption of the Inner Retina" @default.
• W2330794800 cites W1524484817 @default.
• W2330794800 cites W1563688335 @default.
• W2330794800 cites W1840409711 @default.
• W2330794800 cites W190377277 @default.
• W2330794800 cites W1967304265 @default.
• W2330794800 cites W1970717333 @default.
• W2330794800 cites W1972809371 @default.
• W2330794800 cites W1976175245 @default.
• W2330794800 cites W1977287773 @default.
• W2330794800 cites W1979204101 @default.
• W2330794800 cites W1982978147 @default.
• W2330794800 cites W1998355635 @default.
• W2330794800 cites W2003169650 @default.
• W2330794800 cites W2003764456 @default.
• W2330794800 cites W2007290023 @default.
• W2330794800 cites W2010824449 @default.
• W2330794800 cites W2020431068 @default.
• W2330794800 cites W2020656039 @default.
• W2330794800 cites W2024403976 @default.
• W2330794800 cites W2025529600 @default.
• W2330794800 cites W2029260420 @default.
• W2330794800 cites W2034007228 @default.
• W2330794800 cites W2040772514 @default.
• W2330794800 cites W2042873837 @default.
• W2330794800 cites W2050355250 @default.
• W2330794800 cites W2051202572 @default.
• W2330794800 cites W2051809095 @default.
• W2330794800 cites W2053905790 @default.
• W2330794800 cites W2056484039 @default.
• W2330794800 cites W2060261453 @default.
• W2330794800 cites W2063142059 @default.
• W2330794800 cites W2066012392 @default.
• W2330794800 cites W2068513256 @default.
• W2330794800 cites W2069499580 @default.
• W2330794800 cites W2069918336 @default.
• W2330794800 cites W2072280668 @default.
• W2330794800 cites W2074468859 @default.
• W2330794800 cites W2076461829 @default.
• W2330794800 cites W2077072880 @default.
• W2330794800 cites W2080798948 @default.
• W2330794800 cites W2084558001 @default.
• W2330794800 cites W2086244321 @default.
• W2330794800 cites W2090604135 @default.
• W2330794800 cites W2104255545 @default.
• W2330794800 cites W2107082755 @default.
• W2330794800 cites W2117534037 @default.
• W2330794800 cites W2123969911 @default.
• W2330794800 cites W2127869450 @default.
• W2330794800 cites W2130448883 @default.
• W2330794800 cites W2142858404 @default.
• W2330794800 cites W2159725574 @default.
• W2330794800 cites W2316395118 @default.
• W2330794800 cites W2404418562 @default.
• W2330794800 cites W68390617 @default.
• W2330794800 cites W83625337 @default.
• W2330794800 doi "https://doi.org/10.1167/iovs.14-15235" @default.
• W2330794800 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25237158" @default.
• W2330794800 hasPublicationYear "2014" @default.
• W2330794800 type Work @default.
• W2330794800 sameAs 2330794800 @default.
• W2330794800 citedByCount "7" @default.
• W2330794800 countsByYear W23307948002015 @default.
• W2330794800 countsByYear W23307948002016 @default.
• W2330794800 countsByYear W23307948002018 @default.
• W2330794800 countsByYear W23307948002020 @default.
• W2330794800 countsByYear W23307948002021 @default.
• W2330794800 countsByYear W23307948002023 @default.
• W2330794800 crossrefType "journal-article" @default.
• W2330794800 hasAuthorship W2330794800A5013092199 @default.
• W2330794800 hasAuthorship W2330794800A5037098482 @default.
• W2330794800 hasAuthorship W2330794800A5065390232 @default.
• W2330794800 hasAuthorship W2330794800A5065452265 @default.
• W2330794800 hasAuthorship W2330794800A5080146086 @default.
• W2330794800 hasConcept C118487528 @default.
• W2330794800 hasConcept C141071460 @default.
• W2330794800 hasConcept C169760540 @default.
• W2330794800 hasConcept C2777093970 @default.
• W2330794800 hasConcept C2778233873 @default.
• W2330794800 hasConcept C2778257484 @default.
• W2330794800 hasConcept C2780592520 @default.
• W2330794800 hasConcept C2780827179 @default.
• W2330794800 hasConcept C2780837183 @default.
• W2330794800 hasConcept C2781242345 @default.
• W2330794800 hasConcept C2781325737 @default.
• W2330794800 hasConcept C2910004921 @default.
• W2330794800 hasConcept C64731932 @default.
• W2330794800 hasConcept C71924100 @default.
• W2330794800 hasConcept C86803240 @default.

• next