Matches in SemOpenAlex for { <https://semopenalex.org/work/W2330835207> ?p ?o ?g. }
- W2330835207 abstract "derivative of the McDonald-Kreitman test that controls for the slightly deleterious mutations. We find that the rate of adaptive amino acid substitution is positively correlated to both the rates of recombination and mutation. We also find that these correlations are robust to controlling for each other, synonymous codon bias and gene functions related to immune response and testes. We estimate that HRi reduces the rate of adaptive evolution by ~27%. We also show that this fraction depends on a gene's mutation rate; genes with low mutation rates lose ~11% of their adaptive substitutions while genes with high mutation rates lose ~43%. In conclusion, we show that the mutation rate and the rate of recombination, are important modifiers of the rate of adaptive evolution in Drosophila." @default.
- W2330835207 created "2016-06-24" @default.
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- W2330835207 date "2015-01-01" @default.
- W2330835207 modified "2023-09-27" @default.
- W2330835207 title "interference in Drosophila" @default.
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