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- W2330862382 abstract "Background Congenital anomalies – that is, any malformation that occurs in the developing fetus – is one of the major childhood health problems. Objective The aim of the study was to examine the pattern of fetal congenital anomalies in consanguineous marriages. Participants and methods This cross-sectional study included 150 pregnant women from consanguineous marriages with fetal congenital anomalies. They were recruited from the Fetal Medicine Unit at Cairo University Hospital. A structured interview was conducted to collect data on sociodemographic characteristics, medical history, and past obstetric history. An ultrasonographic examination was performed for anatomical scanning of the fetus to screen for the presence of congenital anomalies, in addition to fetal biometry. Results The central nervous system was the most commonly affected system (44%), followed by the musculoskeletal system (23%). Multiple anomalies were detected in 52.7% of the fetuses; they were significantly more common in first-degree consanguineous marriages (P=0.001). The most common types of congenital anomalies among fetuses from consanguineous marriages were cleft palate, bilateral cleft lip, hydronephrosis, and unilateral cleft lip. Conclusion Multiple-system malformations were significantly associated with first-degree consanguineous marriages." @default.
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- W2330862382 date "2014-08-01" @default.
- W2330862382 modified "2023-09-27" @default.
- W2330862382 title "Pattern of fetal congenital anomalies among consanguineous marriages in Cairo University Hospitals" @default.
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- W2330862382 doi "https://doi.org/10.1097/01.ebx.0000452876.69144.04" @default.
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