FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2330961112> ?p ?o ?g. }

• W2330961112 endingPage "P3053" @default.
• W2330961112 startingPage "P3053" @default.
• W2330961112 abstract "Purpose: The DESolve system is a novel Poly-L-Lactide (PLLA)-based scaffold, designed to provide both temporary vessel support along with neointimal suppression, followed by full bioresorption between one and two years. In the present study, we aim to present the first serial optical coherence tomography (OCT) evaluation of the novel PLLA-based novolimus-eluting DESolve bioresorbable scaffold investigated in the DESolve NX study. Methods: The DESolve NX study enrolled 126 patients with single de novo native coronary lesions at 13 sites. A serial (baseline and 6-month follow-up) analysis of the first 25-patient subset who underwent OCT examination will be presented. All OCT images were analyzed by an independent core laboratory at 0.6-mm interval. At baseline, lumen, scaffold, plaque prolapse and incomplete scaffold apposition (ISA) areas were determined. At follow-up, serial changes in lumen and scaffold dimensions and degree of neointimal hyperplasia (NIH) formation on top of the struts will be assessed. Frequency of covered struts and NIH thickness on top of each covered strut will also be examined. OCT imaging end-points were scaffold expansion and structural integrity post-procedure and neointimal obstruction and degree of strut coverage at six-month follow-up. Results: At baseline, overall adequate scaffold expansion (93.75±9.21%) was obtained. A mean of 30.44±5.16 cross-sections were analyzed per scaffold. Mean lumen and scaffold areas measured 6.80±1.35 mm2 and 6.95±1.32 mm2, respectively, with a minimum scaffold area post-procedure of 5.71±1.15 mm2. In average, plaque prolapse accounted for a very small area of lumen reduction post-procedure (0.03±0.02 mm2). ISA was detected at baseline in 9 (36%) scaffolds, but it was in average very small (0.07±0.13 mm2). A total of 9,871 struts were analyzed at baseline, and the frequency of malapposed struts per patient was 0.43±0.98%. All 25 patients have already completed 6-month OCT evaluation, and the images are currently under analysis. The complete serial OCT results will be available at the meeting. Conclusions: The novel PLLA-based novolimus-eluting bioresorbable scaffold demonstrated an excellent acute performance, tolerating very good expansion with virtually no structural deformity concerns. Good vessel wall conformability was also demonstrated, resulting in minimal areas of scaffold malapposition. Six-month OCT analysis is being conducted and will be presented at the meeting." @default.
• W2330961112 created "2016-06-24" @default.
• W2330961112 creator A5006929907 @default.
• W2330961112 creator A5007297814 @default.
• W2330961112 creator A5013878625 @default.
• W2330961112 creator A5021219326 @default.
• W2330961112 creator A5021992802 @default.
• W2330961112 creator A5035989292 @default.
• W2330961112 creator A5039611522 @default.
• W2330961112 creator A5049566889 @default.
• W2330961112 creator A5077826782 @default.
• W2330961112 creator A5079278619 @default.
• W2330961112 date "2013-08-02" @default.
• W2330961112 modified "2023-09-28" @default.
• W2330961112 title "Evaluation of the novel novolimus-eluting bioresorbable vascular scaffold for the treatment of de novo coronary artery stenosis: serial optical coherence tomography analysis of the DESolve NX study" @default.
• W2330961112 doi "https://doi.org/10.1093/eurheartj/eht309.p3053" @default.
• W2330961112 hasPublicationYear "2013" @default.
• W2330961112 type Work @default.
• W2330961112 sameAs 2330961112 @default.
• W2330961112 citedByCount "0" @default.
• W2330961112 crossrefType "journal-article" @default.
• W2330961112 hasAuthorship W2330961112A5006929907 @default.
• W2330961112 hasAuthorship W2330961112A5007297814 @default.
• W2330961112 hasAuthorship W2330961112A5013878625 @default.
• W2330961112 hasAuthorship W2330961112A5021219326 @default.
• W2330961112 hasAuthorship W2330961112A5021992802 @default.
• W2330961112 hasAuthorship W2330961112A5035989292 @default.
• W2330961112 hasAuthorship W2330961112A5039611522 @default.
• W2330961112 hasAuthorship W2330961112A5049566889 @default.
• W2330961112 hasAuthorship W2330961112A5077826782 @default.
• W2330961112 hasAuthorship W2330961112A5079278619 @default.
• W2330961112 hasBestOaLocation W23309611121 @default.
• W2330961112 hasConcept C117866178 @default.
• W2330961112 hasConcept C126322002 @default.
• W2330961112 hasConcept C126838900 @default.
• W2330961112 hasConcept C131631996 @default.
• W2330961112 hasConcept C136229726 @default.
• W2330961112 hasConcept C141071460 @default.
• W2330961112 hasConcept C164705383 @default.
• W2330961112 hasConcept C2776820930 @default.
• W2330961112 hasConcept C2777339539 @default.
• W2330961112 hasConcept C2778095995 @default.
• W2330961112 hasConcept C2778283817 @default.
• W2330961112 hasConcept C2778583881 @default.
• W2330961112 hasConcept C2778818243 @default.
• W2330961112 hasConcept C2780007028 @default.
• W2330961112 hasConcept C2780400711 @default.
• W2330961112 hasConcept C2989005 @default.
• W2330961112 hasConcept C3019225854 @default.
• W2330961112 hasConcept C500558357 @default.
• W2330961112 hasConcept C71924100 @default.
• W2330961112 hasConcept C89429830 @default.
• W2330961112 hasConceptScore W2330961112C117866178 @default.
• W2330961112 hasConceptScore W2330961112C126322002 @default.
• W2330961112 hasConceptScore W2330961112C126838900 @default.
• W2330961112 hasConceptScore W2330961112C131631996 @default.
• W2330961112 hasConceptScore W2330961112C136229726 @default.
• W2330961112 hasConceptScore W2330961112C141071460 @default.
• W2330961112 hasConceptScore W2330961112C164705383 @default.
• W2330961112 hasConceptScore W2330961112C2776820930 @default.
• W2330961112 hasConceptScore W2330961112C2777339539 @default.
• W2330961112 hasConceptScore W2330961112C2778095995 @default.
• W2330961112 hasConceptScore W2330961112C2778283817 @default.
• W2330961112 hasConceptScore W2330961112C2778583881 @default.
• W2330961112 hasConceptScore W2330961112C2778818243 @default.
• W2330961112 hasConceptScore W2330961112C2780007028 @default.
• W2330961112 hasConceptScore W2330961112C2780400711 @default.
• W2330961112 hasConceptScore W2330961112C2989005 @default.
• W2330961112 hasConceptScore W2330961112C3019225854 @default.
• W2330961112 hasConceptScore W2330961112C500558357 @default.
• W2330961112 hasConceptScore W2330961112C71924100 @default.
• W2330961112 hasConceptScore W2330961112C89429830 @default.
• W2330961112 hasIssue "suppl 1" @default.
• W2330961112 hasLocation W23309611121 @default.
• W2330961112 hasOpenAccess W2330961112 @default.
• W2330961112 hasPrimaryLocation W23309611121 @default.
• W2330961112 hasRelatedWork W1968931804 @default.
• W2330961112 hasRelatedWork W2016230813 @default.
• W2330961112 hasRelatedWork W2330961112 @default.
• W2330961112 hasRelatedWork W2396081018 @default.
• W2330961112 hasRelatedWork W2507906041 @default.
• W2330961112 hasRelatedWork W2660200307 @default.
• W2330961112 hasRelatedWork W2743773490 @default.
• W2330961112 hasRelatedWork W3109503504 @default.
• W2330961112 hasRelatedWork W4247432807 @default.
• W2330961112 hasRelatedWork W69359845 @default.
• W2330961112 hasVolume "34" @default.
• W2330961112 isParatext "false" @default.
• W2330961112 isRetracted "false" @default.
• W2330961112 magId "2330961112" @default.
• W2330961112 workType "article" @default.