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- W2331062124 abstract "We have recently developed new Tempo-PEG-RGDs conjugates and have quantitatively examined their antithrombotic and antioxidant capabilities. These compounds were therapeutically beneficial when characterized in both in vitro platelet aggregation assays and a rat model of arterial thrombosis. Moreover, these compounds demonstrated significant protection from organ damage in a rat model of ischemia/reperfusion. Our data indicate that Tempo-PEG-RGDs represent a new class of adjuvants with therapeutic efficacy in acute and transient ischemic damage." @default.
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- W2331062124 date "2012-04-23" @default.
- W2331062124 modified "2023-10-02" @default.
- W2331062124 title "Novel TEMPO-PEG-RGDs Conjugates Remediate Tissue Damage Induced by Acute Limb Ischemia/Reperfusion" @default.
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- W2331062124 doi "https://doi.org/10.1021/jm201381w" @default.
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