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• W2331276238 startingPage "4192" @default.
• W2331276238 abstract "The effect of silk protein with different fibroin/sericin compositions on body weight and lipid metabolism in high fat-fed mice was investigated. The animals were given experimental diets for 6 weeks: normal control (NC), high fat (HF) and high fat diet supplemented with F100 (pure fibroin, HF-F100), F81 (81:19 fibroin/sericin, w/w, HF-F81) or F50 (50:50 fibroin/sericin, w/w, HF-F50). The silk protein-fed mice showed markedly reduced body weight and enhanced lipid profile relative to the HF group. In general, the amount of body fat, triglyceride and total plasma cholesterol levels, atherogenic index and free fatty acid level tended to decrease, while the HDL-cholesterol level increased, with increased amount of sericin in the diet. This hypolipidemic effect was partly due to increased fecal lipid excretion, inhibition of lipogenesis and regulation of adipokine production. These findings illustrate that silk protein, particularly sericin, may be beneficial in the prevention of high fat diet-induced hyperlipidemia and obesity." @default.
• W2331276238 created "2016-06-24" @default.
• W2331276238 creator A5012452722 @default.
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• W2331276238 date "2011-03-08" @default.
• W2331276238 modified "2023-10-13" @default.
• W2331276238 title "Antihyperlipidemic and Body Fat-Lowering Effects of Silk Proteins with Different Fibroin/Sericin Compositions in Mice Fed with High Fat Diet" @default.
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• W2331276238 doi "https://doi.org/10.1021/jf104812g" @default.
• W2331276238 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21384872" @default.
• W2331276238 hasPublicationYear "2011" @default.
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