Matches in SemOpenAlex for { <https://semopenalex.org/work/W2331285959> ?p ?o ?g. }
- W2331285959 abstract "Mood and anxiety disorders are a major burden to the society today but still the pathophysiology behind these disorders is largely unknown and the pharmacotherapy available today is far from sufficient, with relatively low remission rates. Recent results regarding the action of CYP2C19 and CYP2D6 in the CNS suggest associations between suicidality, anxiety and other stress-related disorders and such CYP enzyme polymorphisms. Knowledge about the CNS specific action of these enzymes might in the future provide an increased understanding of the pathogenesis and pathophysiology of these disorders. Here we present an update of the research carried out in human and animal models with focus on the roles of CYP2C19 and CYP2D6 for brain development and function mediated by the metabolism of endogenous compounds." @default.
- W2331285959 created "2016-06-24" @default.
- W2331285959 creator A5012663065 @default.
- W2331285959 creator A5086579034 @default.
- W2331285959 date "2014-01-01" @default.
- W2331285959 modified "2023-10-17" @default.
- W2331285959 title "Pharmacogenomics of Cytochrome P450 Dependent Metabolism of Endogenous Compounds: Implications for Behavior, Psychopathology and Treatment" @default.
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- W2331285959 doi "https://doi.org/10.4172/2153-0645.1000127" @default.
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