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- W2331306877 endingPage "585" @default.
- W2331306877 startingPage "576" @default.
- W2331306877 abstract "Abstract Background. Treatment options for women with metastatic, persistent, or recurrent cervical cancer are limited and thus the disease portends a poor prognosis. It is critical to understand the pathophysiology of cervical cancer to better delineate therapeutic targets. The development of antiangiogenic therapies and their subsequent analysis in rigorous therapeutic trials have redefined current management strategies and is an exciting area of current exploration. Results. Translational trials have furthered the understanding of molecular determinants of angiogenesis. Phase II trials have shown promising trends with developing antiangiogenic therapies. A practice-changing phase III trial has recently been published. Given the potential benefits and different toxicity spectrum compared with standard cytotoxic chemotherapy, antiangiogenic options are under active investigation for this vulnerable patient population. Emerging data are promising for other antiangiogenic-directed therapeutics, as well as cervical cancer molecular biomarkers to guide diagnosis and treatment. Conclusion. Antiangiogenic therapies have evolved during the past 20 years and remain an exciting area of current exploration." @default.
- W2331306877 created "2016-06-24" @default.
- W2331306877 creator A5054055388 @default.
- W2331306877 creator A5055050872 @default.
- W2331306877 date "2016-03-29" @default.
- W2331306877 modified "2023-10-16" @default.
- W2331306877 title "Clinical Trials of Antiangiogenesis Therapy in Recurrent/Persistent and Metastatic Cervical Cancer" @default.
- W2331306877 cites W1489093460 @default.
- W2331306877 cites W1526291802 @default.
- W2331306877 cites W1527544276 @default.
- W2331306877 cites W1568869896 @default.
- W2331306877 cites W1756949381 @default.
- W2331306877 cites W1767781328 @default.
- W2331306877 cites W1886850372 @default.
- W2331306877 cites W1903265209 @default.
- W2331306877 cites W1955739292 @default.
- W2331306877 cites W1964256075 @default.
- W2331306877 cites W1964797240 @default.
- W2331306877 cites W1968585778 @default.
- W2331306877 cites W1968812234 @default.
- W2331306877 cites W1969558402 @default.
- W2331306877 cites W1970895498 @default.
- W2331306877 cites W1970939192 @default.
- W2331306877 cites W1973639059 @default.
- W2331306877 cites W1979107417 @default.
- W2331306877 cites W1983008695 @default.
- W2331306877 cites W1986480595 @default.
- W2331306877 cites W1987084841 @default.
- W2331306877 cites W1992202959 @default.
- W2331306877 cites W1992778754 @default.
- W2331306877 cites W1992890934 @default.
- W2331306877 cites W1994000111 @default.
- W2331306877 cites W1995227659 @default.
- W2331306877 cites W1996050196 @default.
- W2331306877 cites W1997347278 @default.
- W2331306877 cites W2003649909 @default.
- W2331306877 cites W2004262699 @default.
- W2331306877 cites W2007672298 @default.
- W2331306877 cites W2008258644 @default.
- W2331306877 cites W2010348402 @default.
- W2331306877 cites W2011814551 @default.
- W2331306877 cites W2014356708 @default.
- W2331306877 cites W2015919139 @default.
- W2331306877 cites W2016020717 @default.
- W2331306877 cites W2019994604 @default.
- W2331306877 cites W2022379251 @default.
- W2331306877 cites W2034223817 @default.
- W2331306877 cites W2035433983 @default.
- W2331306877 cites W2037429429 @default.
- W2331306877 cites W2043715866 @default.
- W2331306877 cites W2046344327 @default.
- W2331306877 cites W2048678026 @default.
- W2331306877 cites W2049454219 @default.
- W2331306877 cites W2050062343 @default.
- W2331306877 cites W2050415197 @default.
- W2331306877 cites W2052883386 @default.
- W2331306877 cites W2053068747 @default.
- W2331306877 cites W2056733994 @default.
- W2331306877 cites W2058150352 @default.
- W2331306877 cites W2058820448 @default.
- W2331306877 cites W2066485594 @default.
- W2331306877 cites W2073660691 @default.
- W2331306877 cites W2074622849 @default.
- W2331306877 cites W2079147576 @default.
- W2331306877 cites W2084106534 @default.
- W2331306877 cites W2085748209 @default.
- W2331306877 cites W2088289664 @default.
- W2331306877 cites W2090094486 @default.
- W2331306877 cites W2100669312 @default.
- W2331306877 cites W2100756525 @default.
- W2331306877 cites W2101196984 @default.
- W2331306877 cites W2102915986 @default.
- W2331306877 cites W2106787323 @default.
- W2331306877 cites W2108701553 @default.
- W2331306877 cites W2109515997 @default.
- W2331306877 cites W2110206480 @default.
- W2331306877 cites W2111080918 @default.
- W2331306877 cites W2120675172 @default.
- W2331306877 cites W2126275851 @default.
- W2331306877 cites W2134953299 @default.
- W2331306877 cites W2141046053 @default.
- W2331306877 cites W2142719896 @default.
- W2331306877 cites W2145835533 @default.
- W2331306877 cites W2147626573 @default.
- W2331306877 cites W2150714759 @default.
- W2331306877 cites W2157769714 @default.
- W2331306877 cites W2159424472 @default.
- W2331306877 cites W2166573361 @default.
- W2331306877 cites W2170781431 @default.
- W2331306877 cites W2170825221 @default.
- W2331306877 cites W2194099451 @default.
- W2331306877 cites W2201394834 @default.
- W2331306877 cites W2235523093 @default.
- W2331306877 cites W2259227992 @default.
- W2331306877 cites W2339896458 @default.
- W2331306877 cites W2341443030 @default.
- W2331306877 cites W2460441586 @default.
- W2331306877 cites W4232706348 @default.