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- W2331388662 abstract "Introduction: Left ventricular non compaction (LVNC) is a rare cardiomyopathy. Differential diagnosis from other myocardial disorders such as hypertrophic cardiomyopathy (HCM) may be challenging. It has been described that myocardial strain helps to differentiate LVNC from dilated cardiomyopathy (DCM) and controls. Our purpose is to compare deformation and rotation of LVNC with HCM and controls. Methods: We included 27 patients with LVNC (40.7% with EF≥45%), diagnosed by echocardiography (n=5), magnetic resonance imaging (n=6) or both tests (n=16), 43 HCM and 15 controls. Longitudinal strain (LStrain) was evaluated using 12 individual segments from 2 and 4 chamber views. Parasternal short axis view was used for evaluation of basal and apical rotation (R). 12 individual segments were analyzed for LStrain evaluation. In the LVNC group 255 individual segments were studied, of whom 59 were not compacted (23.1%). Results: L Strain was reduced in LVNC and HCM compared to controls (table 1). A reduction in apical R and torsion was specifically observed in the LVNC patients. Within this group, L Strain and apical rotation values were even lower when EF was <45%, with an uniform clockwise basal and apical R. LVNC, HCM and controls: Comparative 1: LVNC compared with controls; 2: LVNC compared with HCM. NS, Non significant; R, Rotayion; LVTDD, Left ventricle telediastolic diameter; LA, Left atrium. Conclusions: L strain is reduced in both cardiomyopathies, but reduction of apical R is specifically observed in LVNC. This could respond to the lack of compaction in mid and apical segments during embryonic development of the heart. Future applications of this technique include differential diagnosis with HCM and early detection of myocardial damage in disease carriers." @default.
- W2331388662 created "2016-06-24" @default.
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- W2331388662 date "2013-08-02" @default.
- W2331388662 modified "2023-09-26" @default.
- W2331388662 title "2D Strain in left ventricular non compaction: the clue for differential diagnosis with hypertrophic cardiomyopathy" @default.
- W2331388662 doi "https://doi.org/10.1093/eurheartj/eht309.p2995" @default.
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