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- W2331402382 abstract "Introduction: The epithelial Na+ channel (ENaC) and the cystic fibrosis transmembrane conductance regulator (CFTR) are important ion channels in airway epithelial cells. Together they play a crucial role in airway fluid homeostasis and there is evidence that malfunction is associated with the phenotype of cystic fibrosis lung disease. In mice airway epithelia luminal acetylcholine (ACh) has been identified to activate Cl− secretion (Hollenhorst et al. Br J Pharmacol 2012). The present study investigates whether the ENaC or the CFTR is a putative target of luminal ACh in the airways of pigs." @default.
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- W2331402382 date "2013-08-01" @default.
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- W2331402382 title "Effect of luminal acetylcholine on ENaC- and CFTR-activity in porcine airway epithelium" @default.
- W2331402382 doi "https://doi.org/10.1016/j.autneu.2013.05.138" @default.
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