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- W2331402596 abstract "Among the conflicts of modern life is that faced by many educated women between the desire to pursue a professional career and the demands of their potential maternal role. Some resolve this by deferring having children. This deferment, coupled with an increased awareness of birth defects generally and of the problems faced by older mothers, leads to an increasing number of queries to genetic advisory services, family doctors, obstetricians, and family planning centres, as to the specific risks in reproduction by older parents. The appreciable risk of death in childbed of earlier days is no longer with us, thanks to modern obstetric techniques. But the child morbidity due to congenital and genetic disorders, already appreciable (Roberts, Chavez & Court, 1970; Roberts, 1975) and increasing both proportionately and absolutely, and the evidence that some of these increase in incidence with age, mean that there is a real basis for the enquirers' concern. The following review of the ways in which parental ageing affects the incidence of such disorders, and of the mechanisms that appear to be responsible, places the increased risks in perspective." @default.
- W2331402596 created "2016-06-24" @default.
- W2331402596 creator A5062072598 @default.
- W2331402596 date "1979-01-01" @default.
- W2331402596 modified "2023-09-27" @default.
- W2331402596 title "Genetics and ageing in man" @default.
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- W2331402596 doi "https://doi.org/10.1017/s0021932000024378" @default.
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