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- W2331432503 abstract "Video-assisted thoracic surgery (VATS) is an emerging alternative for selected non-small cell lung cancer (NSCLC) patients. In this cost-effectiveness analysis, we used patient-level data to compare VATS and open surgery for newly diagnosed stage I NSCLC patients. Using information from the cancer registry, mortality data, and claims data in the Collaboration Center of Health Information Application database in Taiwan, we identified patients with newly diagnosed stage I NSCLC received primary lung resection in 2007 and defined the index date as the date of admission for the index surgery. We compared the cost, effectiveness, and cost-effectiveness of VATS vs. open surgery within 1 year after the index date in this retrospective cohort study. The study was conducted from a payor's (i.e.,Taiwanese National Health Insurance Program) perspective. All costs were converted to 2011 US dollars using the local consumer price index and purchasing power parity. We included patient sociodemographics factors, provider characteristics, and clinical variables as explanatory variables. We used the propensity score bin bootstrapping method for 1000 times to obtain the distribution of the incremental cost-effectiveness ratio (ICER, in US dollars/life-years (USD/LY)) and to get a better matching of case vs. control by using the above explanatory variables. We identified 329 patients with newly diagnosis NSCLC; 114 patients received VATS. VATS is associated with higher mean effectiveness (0.972 vs. 0.965 LY) and higher cost ($19,679 vs. $18,996 USD). The estimated mean ICER was $765,19/LY, and the probability that VATS is more cost-effective at $50,000-100,000/LY is 41-56%. This short-term CEA suggested that for newly diagnosed stage I NSCLC patients VATS is likely to be cost-effective when compared to open surgery. The result should be interpreted with caution because of potential endogeneity in treatment selection, and the small absolute difference and wide confidence interval observed in our data." @default.
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- W2331432503 date "2012-06-01" @default.
- W2331432503 modified "2023-09-27" @default.
- W2331432503 title "PSU22 Cost-Effectiveness Analysis of Video-Assisted Thoracic Surgery vs. Open Surgery for Patients with Newly Diagnosed Stage I Non-Small Cell Lung Cancer" @default.
- W2331432503 doi "https://doi.org/10.1016/j.jval.2012.03.425" @default.
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