FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2331693462> ?p ?o ?g. }

• W2331693462 endingPage "1221" @default.
• W2331693462 startingPage "1214" @default.
• W2331693462 abstract "Background The treatment of children with T‐cell lymphoblastic lymphoma (T‐LBL) and precursor B‐cell lymphoblastic lymphoma (pB‐LBL) has improved during the last decades. However, patients with relapsed or refractory lymphomas still have a poor prognosis. Methods We report the characteristics and evolution of T‐LBL and pB‐LBL relapses in two multicenter prospective studies (LMT 96, European Organization for Research and Treatment of Cancer 58951). Results From 1997 to 2008, 194 patients were included in these studies (157 T‐LBL; 37 pB‐LBL); among them, 23 patients underwent relapse or progression (18 T‐LBL and 5 pB‐LBL). The median age was 7.7 years (range 1.4–16.3). The survival rate at 8 years was 8.7% (21 deaths). The median time from diagnosis to relapse was 9 months [1–69] and 11 months [1–45] for T‐LBL and pB‐LBL, respectively. Twenty‐two patients received a second‐line treatment but remission was achieved in only seven patients. In 10 patients, intensification with hematopoietic stem cell transplantation (HSCT) was performed and four of them had a second relapse. Two patients still alive had T‐LBL, experienced relapses 15 and 69 months after diagnosis, and received HSCT. Relapse during the intensive phase and second‐line treatment without HSCT were identified as risk factors for bad prognosis ( P = 0.01). Conclusions The results of second‐line treatment, including intensive chemotherapy and HSCT, show that salvage treatment is still disappointing in controlling refractory forms. Early identification of patients at high risk of relapse is mandatory, allowing earlier intensification. Valid prognostic parameters, such as biological markers, are needed. International cooperation is warranted to collect more data on these rare diagnoses." @default.
• W2331693462 created "2016-06-24" @default.
• W2331693462 creator A5000382317 @default.
• W2331693462 creator A5015622625 @default.
• W2331693462 creator A5056903988 @default.
• W2331693462 creator A5061565715 @default.
• W2331693462 creator A5071405091 @default.
• W2331693462 creator A5073306699 @default.
• W2331693462 date "2016-04-01" @default.
• W2331693462 modified "2023-09-27" @default.
• W2331693462 title "Relapsed or Refractory Lymphoblastic Lymphoma in Children: Results and Analysis of 23 Patients in the EORTC 58951 and the LMT96 Protocols" @default.
• W2331693462 cites W1501225775 @default.
• W2331693462 cites W1519793899 @default.
• W2331693462 cites W1641010126 @default.
• W2331693462 cites W1970909520 @default.
• W2331693462 cites W1975053487 @default.
• W2331693462 cites W1977096590 @default.
• W2331693462 cites W1981060857 @default.
• W2331693462 cites W1989810138 @default.
• W2331693462 cites W1995022455 @default.
• W2331693462 cites W1999105034 @default.
• W2331693462 cites W1999637438 @default.
• W2331693462 cites W2006188256 @default.
• W2331693462 cites W2016085357 @default.
• W2331693462 cites W2019314170 @default.
• W2331693462 cites W2027763899 @default.
• W2331693462 cites W2053218407 @default.
• W2331693462 cites W2054507081 @default.
• W2331693462 cites W2064933040 @default.
• W2331693462 cites W2068619849 @default.
• W2331693462 cites W2080092242 @default.
• W2331693462 cites W2093958150 @default.
• W2331693462 cites W2095871627 @default.
• W2331693462 cites W2097501739 @default.
• W2331693462 cites W2104398039 @default.
• W2331693462 cites W2115482777 @default.
• W2331693462 cites W2135817344 @default.
• W2331693462 cites W2137042680 @default.
• W2331693462 cites W2141819662 @default.
• W2331693462 cites W2143502805 @default.
• W2331693462 cites W2150629538 @default.
• W2331693462 cites W2152450140 @default.
• W2331693462 cites W2156377069 @default.
• W2331693462 cites W2167086064 @default.
• W2331693462 cites W2170163717 @default.
• W2331693462 cites W2171801361 @default.
• W2331693462 cites W2310146029 @default.
• W2331693462 cites W4293241248 @default.
• W2331693462 doi "https://doi.org/10.1002/pbc.25990" @default.
• W2331693462 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/27037853" @default.
• W2331693462 hasPublicationYear "2016" @default.
• W2331693462 type Work @default.
• W2331693462 sameAs 2331693462 @default.
• W2331693462 citedByCount "19" @default.
• W2331693462 countsByYear W23316934622017 @default.
• W2331693462 countsByYear W23316934622019 @default.
• W2331693462 countsByYear W23316934622020 @default.
• W2331693462 countsByYear W23316934622021 @default.
• W2331693462 countsByYear W23316934622022 @default.
• W2331693462 countsByYear W23316934622023 @default.
• W2331693462 crossrefType "journal-article" @default.
• W2331693462 hasAuthorship W2331693462A5000382317 @default.
• W2331693462 hasAuthorship W2331693462A5015622625 @default.
• W2331693462 hasAuthorship W2331693462A5056903988 @default.
• W2331693462 hasAuthorship W2331693462A5061565715 @default.
• W2331693462 hasAuthorship W2331693462A5071405091 @default.
• W2331693462 hasAuthorship W2331693462A5073306699 @default.
• W2331693462 hasBestOaLocation W23316934621 @default.
• W2331693462 hasConcept C121332964 @default.
• W2331693462 hasConcept C126322002 @default.
• W2331693462 hasConcept C142424586 @default.
• W2331693462 hasConcept C143998085 @default.
• W2331693462 hasConcept C187212893 @default.
• W2331693462 hasConcept C203014093 @default.
• W2331693462 hasConcept C2776090121 @default.
• W2331693462 hasConcept C2776694085 @default.
• W2331693462 hasConcept C2777408962 @default.
• W2331693462 hasConcept C2777478502 @default.
• W2331693462 hasConcept C2779338263 @default.
• W2331693462 hasConcept C2780775027 @default.
• W2331693462 hasConcept C2911091166 @default.
• W2331693462 hasConcept C71924100 @default.
• W2331693462 hasConcept C87355193 @default.
• W2331693462 hasConcept C8891405 @default.
• W2331693462 hasConceptScore W2331693462C121332964 @default.
• W2331693462 hasConceptScore W2331693462C126322002 @default.
• W2331693462 hasConceptScore W2331693462C142424586 @default.
• W2331693462 hasConceptScore W2331693462C143998085 @default.
• W2331693462 hasConceptScore W2331693462C187212893 @default.
• W2331693462 hasConceptScore W2331693462C203014093 @default.
• W2331693462 hasConceptScore W2331693462C2776090121 @default.
• W2331693462 hasConceptScore W2331693462C2776694085 @default.
• W2331693462 hasConceptScore W2331693462C2777408962 @default.
• W2331693462 hasConceptScore W2331693462C2777478502 @default.
• W2331693462 hasConceptScore W2331693462C2779338263 @default.
• W2331693462 hasConceptScore W2331693462C2780775027 @default.
• W2331693462 hasConceptScore W2331693462C2911091166 @default.
• W2331693462 hasConceptScore W2331693462C71924100 @default.

• next