FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2331694860> ?p ?o ?g. }

• W2331694860 endingPage "12628" @default.
• W2331694860 startingPage "12618" @default.
• W2331694860 abstract "The polar lipid fraction E (PLFE) isolated from the thermoacidophilic archaeon Sulfolobus acidocaldarius contains exclusively bipolar tetraether lipids, which are able to form extraordinarily stable vesicular membranes against a number of chemical, physical, and mechanical stressors. PLFE liposomes have thus been considered appealing biomaterials holding great promise for biotechnology applications such as drug delivery and biosensing. Here we demonstrated that PLFE can also form free-standing “planar” membranes on micropores (∼100 μm) of polydimethylsiloxane (PDMS) thin films embedded in printed circuit board (PCB)-based fluidics. To build this device, two novel approaches were employed: (i) an S1813 sacrificial layer was used to facilitate the fabrication of the PDMS thin film, and (ii) oxygen plasma treatment was utilized to conveniently bond the PDMS thin film to the PCB board and the PDMS fluidic chamber. Using electrochemical impedance spectroscopy, we found that the dielectric properties of PLFE planar membranes suspended on the PDMS films are distinctly different from those obtained from diester lipid and triblock copolymer membranes. In addition to resistance (R) and capacitance (C) that were commonly seen in all the membranes examined, PLFE planar membranes showed an inductance (L) component. Furthermore, PLFE planar membranes displayed a relatively large membrane resistance, suggesting that, among the membranes examined, PLFE planar membrane would be a better matrix for studying channel proteins and transmembrane events. PLFE planar membranes also exhibited a sharp decrease in phase angle with the frequency of the input AC signal at ∼1 MHz, which could be utilized to develop sensors for monitoring PLFE membrane integrity in fluidics. Since the stability of free-standing planar lipid membranes increases with increasing membrane packing tightness and PLFE lipid membranes are more tightly packed than those made of diester lipids, PLFE free-standing planar membranes are expected to be considerably stable. All these salient features make PLFE planar membranes particularly attractive for model studies of channel proteins and transmembrane events and for high-throughput drug screening and artificial photosynthesis. This work can be extended to nanopores of PDMS thin films in microfluidics and eventually aid in membrane-based new lab-on-a-chip applications." @default.
• W2331694860 created "2016-06-24" @default.
• W2331694860 creator A5044037372 @default.
• W2331694860 creator A5050435612 @default.
• W2331694860 creator A5055276776 @default.
• W2331694860 creator A5061378680 @default.
• W2331694860 creator A5062597829 @default.
• W2331694860 creator A5064443910 @default.
• W2331694860 creator A5070487893 @default.
• W2331694860 creator A5073275300 @default.
• W2331694860 date "2014-06-30" @default.
• W2331694860 modified "2023-10-17" @default.
• W2331694860 title "Design, Fabrication, and Characterization of Archaeal Tetraether Free-Standing Planar Membranes in a PDMS- and PCB-Based Fluidic Platform" @default.
• W2331694860 cites W1969245917 @default.
• W2331694860 cites W1973461864 @default.
• W2331694860 cites W1975369234 @default.
• W2331694860 cites W1979379045 @default.
• W2331694860 cites W1979817264 @default.
• W2331694860 cites W1981966196 @default.
• W2331694860 cites W1984099781 @default.
• W2331694860 cites W1988026968 @default.
• W2331694860 cites W1989656505 @default.
• W2331694860 cites W1993961556 @default.
• W2331694860 cites W2004485719 @default.
• W2331694860 cites W2009808875 @default.
• W2331694860 cites W2010688654 @default.
• W2331694860 cites W2010899142 @default.
• W2331694860 cites W2022493422 @default.
• W2331694860 cites W2024205812 @default.
• W2331694860 cites W2025330804 @default.
• W2331694860 cites W2031764654 @default.
• W2331694860 cites W2039323342 @default.
• W2331694860 cites W2040329560 @default.
• W2331694860 cites W2042938243 @default.
• W2331694860 cites W2047867072 @default.
• W2331694860 cites W2051772348 @default.
• W2331694860 cites W2052761334 @default.
• W2331694860 cites W2052858774 @default.
• W2331694860 cites W2055553028 @default.
• W2331694860 cites W2058254498 @default.
• W2331694860 cites W2066338596 @default.
• W2331694860 cites W2067315563 @default.
• W2331694860 cites W2067575569 @default.
• W2331694860 cites W2068219225 @default.
• W2331694860 cites W2068254904 @default.
• W2331694860 cites W2068870765 @default.
• W2331694860 cites W2069832711 @default.
• W2331694860 cites W2071592915 @default.
• W2331694860 cites W2073446128 @default.
• W2331694860 cites W2082768551 @default.
• W2331694860 cites W2086013060 @default.
• W2331694860 cites W2086410428 @default.
• W2331694860 cites W2087223048 @default.
• W2331694860 cites W2087817937 @default.
• W2331694860 cites W2088477826 @default.
• W2331694860 cites W2090527060 @default.
• W2331694860 cites W2093203118 @default.
• W2331694860 cites W2093462286 @default.
• W2331694860 cites W2093713392 @default.
• W2331694860 cites W2100894252 @default.
• W2331694860 cites W2103191515 @default.
• W2331694860 cites W2106847663 @default.
• W2331694860 cites W2107542980 @default.
• W2331694860 cites W2118990661 @default.
• W2331694860 cites W2121768393 @default.
• W2331694860 cites W2122092359 @default.
• W2331694860 cites W2123160008 @default.
• W2331694860 cites W2127639138 @default.
• W2331694860 cites W2130902338 @default.
• W2331694860 cites W2142630668 @default.
• W2331694860 cites W2146739168 @default.
• W2331694860 cites W2150355725 @default.
• W2331694860 cites W2153901455 @default.
• W2331694860 cites W2170522824 @default.
• W2331694860 cites W2330510153 @default.
• W2331694860 cites W4255476841 @default.
• W2331694860 doi "https://doi.org/10.1021/am502613x" @default.
• W2331694860 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24937508" @default.
• W2331694860 hasPublicationYear "2014" @default.
• W2331694860 type Work @default.
• W2331694860 sameAs 2331694860 @default.
• W2331694860 citedByCount "16" @default.
• W2331694860 countsByYear W23316948602015 @default.
• W2331694860 countsByYear W23316948602017 @default.
• W2331694860 countsByYear W23316948602018 @default.
• W2331694860 countsByYear W23316948602019 @default.
• W2331694860 countsByYear W23316948602021 @default.
• W2331694860 countsByYear W23316948602022 @default.
• W2331694860 countsByYear W23316948602023 @default.
• W2331694860 crossrefType "journal-article" @default.
• W2331694860 hasAuthorship W2331694860A5044037372 @default.
• W2331694860 hasAuthorship W2331694860A5050435612 @default.
• W2331694860 hasAuthorship W2331694860A5055276776 @default.
• W2331694860 hasAuthorship W2331694860A5061378680 @default.
• W2331694860 hasAuthorship W2331694860A5062597829 @default.
• W2331694860 hasAuthorship W2331694860A5064443910 @default.
• W2331694860 hasAuthorship W2331694860A5070487893 @default.
• W2331694860 hasAuthorship W2331694860A5073275300 @default.

• next