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- W2331822466 abstract "Purpose: Recanalization of chronic total occlusion (CTO) remains a major challenge in interventional cardiology. The objective of this pooled analysis was to evaluate the safety and effectiveness of XIENCE V when treating CTO lesions.Methods: Both XIENCE V USA and SPIRIT V are large, prospective, multicenter, post-approval, real-world studies conducted in the US and 29 countries in Europe and Asia Pacific. Baseline and 1-year clinical outcomes were compared between patients with and without treatment of at least 1 CTO lesion during the index procedure.Results: Baseline characteristics and clinical outcomes are summarized in the table.View this table:Table 1. Clinical results in patients with and without CTO lesions treatedConclusions: The one-year stent thrombosis rate and other clinical event rates were low in the CTO cohort and were comparable to those of the non-CTO cohort despite an increase in lesion complexity. These results demonstrate the safety and effectiveness of XIENCE V in real-world CTO treatment. However, despite the large population enrolled in both studies, the sample size of the CTO cohort was relatively small. Therefore, results obtained from this pooled analysis are yet to be confirmed in a large, prospective, randomized study." @default.
- W2331822466 created "2016-06-24" @default.
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- W2331822466 date "2013-08-02" @default.
- W2331822466 modified "2023-09-26" @default.
- W2331822466 title "Clinical outcomes in treatment of chronic total occlusions with the XIENCE V everolimus-eluting stent system in real-world patients: one-year pooled results from the XIENCE V USA and SPIRIT V studies" @default.
- W2331822466 doi "https://doi.org/10.1093/eurheartj/eht308.p1225" @default.
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