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- W2331837321 abstract "Carriers of a ring chromosome 22 are mentally retarded and show variable facial dysmorphism. They may also present with features of neurofibromatosis type II (NF2) such as vestibular schwannomas and multiple meningiomas. In these cases, tumourigenesis has been suspected to be caused by the loss of both alleles of the NF2 gene, a tumour suppressor localized in 22q12.2." @default.
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- W2331837321 date "2012-04-01" @default.
- W2331837321 modified "2023-10-14" @default.
- W2331837321 title "Ring chromosome 22 and neurofibromatosis type II: proof of two hit model for the loss of the NF2 gene in the development of meningioma" @default.
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- W2331837321 doi "https://doi.org/10.1055/s-0032-1307128" @default.
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