Matches in SemOpenAlex for { <https://semopenalex.org/work/W2331934575> ?p ?o ?g. }
- W2331934575 endingPage "819" @default.
- W2331934575 startingPage "809" @default.
- W2331934575 abstract "Vogt–Koyanagi–Harada syndrome (VKH) is a bilateral, diffuse granulomatous uveitis associated with neurological, audiovestibular, and dermatological systems. The primary pathogenesis is T-cell-mediated autoimmune response directed towards melanocyte or melanocyte-associated antigens causing inflammation of the choroidal layer. This phenomenon usually leads to diffuse inflammatory conditions throughout most parts of eye before ocular complications ensue. The diagnosis is achieved mainly by clinical features according to the revised diagnostic criteria of VKH published in 2001, without confirmatory serologic tests as a requirement. However, ancillary tests, especially multimodal imaging, can reliably provide supportive evidence for the diagnosis of early cases, atypical presentations, and evaluation of management. Prompt treatment with systemic corticosteroids and early non-steroidal immunosuppressive drug therapy can lessen visually threatening ocular complications and bring about good visual recovery. Close monitoring warrants visual stabilization from disease recurrence and ocular complications. This article review aims not only to update comprehensive knowledge regarding VKH but also to emphasize three major perspectives of VKH: immunogenetics as the major pathogenesis of the disease, multimodal imaging, and therapeutic options. The role of anti-vascular endothelial growth factor therapy and drug-induced VKH is also provided." @default.
- W2331934575 created "2016-06-24" @default.
- W2331934575 creator A5012967098 @default.
- W2331934575 creator A5032044514 @default.
- W2331934575 creator A5040566981 @default.
- W2331934575 creator A5073077641 @default.
- W2331934575 date "2016-08-01" @default.
- W2331934575 modified "2023-10-10" @default.
- W2331934575 title "Vogt–Koyanagi–Harada syndrome: Perspectives for immunogenetics, multimodal imaging, and therapeutic options" @default.
- W2331934575 cites W1005670991 @default.
- W2331934575 cites W1587485596 @default.
- W2331934575 cites W1713341411 @default.
- W2331934575 cites W172362473 @default.
- W2331934575 cites W1920907179 @default.
- W2331934575 cites W1964479859 @default.
- W2331934575 cites W1964527651 @default.
- W2331934575 cites W1968542363 @default.
- W2331934575 cites W1969763227 @default.
- W2331934575 cites W1970256214 @default.
- W2331934575 cites W1970353411 @default.
- W2331934575 cites W197051116 @default.
- W2331934575 cites W1974328816 @default.
- W2331934575 cites W1979701001 @default.
- W2331934575 cites W1980160668 @default.
- W2331934575 cites W1980715244 @default.
- W2331934575 cites W1981884254 @default.
- W2331934575 cites W1982057257 @default.
- W2331934575 cites W1982118046 @default.
- W2331934575 cites W1984030154 @default.
- W2331934575 cites W1986811069 @default.
- W2331934575 cites W1988249297 @default.
- W2331934575 cites W1989262657 @default.
- W2331934575 cites W1989730189 @default.
- W2331934575 cites W1990051308 @default.
- W2331934575 cites W1995835630 @default.
- W2331934575 cites W1996471125 @default.
- W2331934575 cites W1999616114 @default.
- W2331934575 cites W2004548782 @default.
- W2331934575 cites W2007205635 @default.
- W2331934575 cites W2009212522 @default.
- W2331934575 cites W2011540337 @default.
- W2331934575 cites W2016786879 @default.
- W2331934575 cites W2017173083 @default.
- W2331934575 cites W2017877160 @default.
- W2331934575 cites W2018454598 @default.
- W2331934575 cites W2019615790 @default.
- W2331934575 cites W2019999154 @default.
- W2331934575 cites W2021773380 @default.
- W2331934575 cites W2021898089 @default.
- W2331934575 cites W2022313305 @default.
- W2331934575 cites W2023980007 @default.
- W2331934575 cites W2027090790 @default.
- W2331934575 cites W2029023438 @default.
- W2331934575 cites W2029207164 @default.
- W2331934575 cites W2034207514 @default.
- W2331934575 cites W2034574374 @default.
- W2331934575 cites W2035372539 @default.
- W2331934575 cites W2035784497 @default.
- W2331934575 cites W2036527794 @default.
- W2331934575 cites W2036941085 @default.
- W2331934575 cites W2037319072 @default.
- W2331934575 cites W2038649753 @default.
- W2331934575 cites W2041010053 @default.
- W2331934575 cites W2041221340 @default.
- W2331934575 cites W2045189742 @default.
- W2331934575 cites W2046869790 @default.
- W2331934575 cites W2050337641 @default.
- W2331934575 cites W2050845608 @default.
- W2331934575 cites W2051246867 @default.
- W2331934575 cites W2053475865 @default.
- W2331934575 cites W2057846729 @default.
- W2331934575 cites W2058805950 @default.
- W2331934575 cites W2059083047 @default.
- W2331934575 cites W2060703090 @default.
- W2331934575 cites W2061217789 @default.
- W2331934575 cites W2063897960 @default.
- W2331934575 cites W2064813224 @default.
- W2331934575 cites W2065588725 @default.
- W2331934575 cites W2066633086 @default.
- W2331934575 cites W2068042136 @default.
- W2331934575 cites W2071406464 @default.
- W2331934575 cites W2074078757 @default.
- W2331934575 cites W2074194456 @default.
- W2331934575 cites W2075332893 @default.
- W2331934575 cites W2075981272 @default.
- W2331934575 cites W2076783027 @default.
- W2331934575 cites W2077330797 @default.
- W2331934575 cites W2078880902 @default.
- W2331934575 cites W2079431340 @default.
- W2331934575 cites W2079584011 @default.
- W2331934575 cites W2082106898 @default.
- W2331934575 cites W2084296063 @default.
- W2331934575 cites W2085964720 @default.
- W2331934575 cites W2086155155 @default.
- W2331934575 cites W2086539844 @default.
- W2331934575 cites W2086870363 @default.
- W2331934575 cites W2087994722 @default.
- W2331934575 cites W2089363763 @default.