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- W2332091895 abstract "Thirteen derivatives of hydroxypyruvaldehyde phenylosazone were tested for effects on bovine erythrocyte membrane. Six drugs, including hydroxypyruvaldehyde phenylosazone itself and the o-CH3, m-CH3, p-CH3, o-Cl and p-Cl derivatives, increased the stability of bovine erythrocyte membrane to hypotonic shock ; the other derivatives with highter molecular weights were essentially without effect. Observations by scanning electron microscopy indicated that non-substituted, m-CH3 and o-Cl hydroxypyruvaldehyde phenylosazones caused extrusion of the erythrocyte surface, whereas o-CH3, p-CH3 and p-Cl derivatives caused invagination of the erythrocyte membrane. The p-Cl derivative can be adsorbed onto, or incorporated into the bovine erythrocyte membrane." @default.
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- W2332091895 date "1982-01-01" @default.
- W2332091895 modified "2023-09-25" @default.
- W2332091895 title "Effects of derivatives of hydroxypyruvaldehyde phenylosazone on bovine erythrocyte membrane. I. Influence on the osmotic fragility and morphology." @default.
- W2332091895 doi "https://doi.org/10.1248/cpb.30.959" @default.
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