Matches in SemOpenAlex for { <https://semopenalex.org/work/W2332153973> ?p ?o ?g. }
- W2332153973 endingPage "2833" @default.
- W2332153973 startingPage "2822" @default.
- W2332153973 abstract "Two new DNA-mimicking brush polymers were synthesized: poly[oxy(11-(3-(9-adeninyl)propionato)-undecanyl-1-thiomethyl)ethylene] (PECH-AP) and poly[oxy(11-(5-(9-adenylethyloxy)-4-oxopentanoato)undecanyl-1-thiomethyl)ethylene] (PECH-AS). These polymers were found to be thermally stable up to 220 °C and could be applied easily by conventional coating processes to produce good quality films. Interestingly, both brush polymers formed molecular multibilayer structures to provide an adenine-rich surface. Despite the structural similarities, PECH-AS surprisingly exhibited higher hydrophilicity and better water sorption properties than PECH-AP. These differences were attributed to the chemical structures in the bristles of the polymers. The adenine-rich surfaces of the polymer films demonstrated selective protein adsorption, suppressed bacterial adherence, facilitated HEp-2 cell adhesion, and exhibited good biocompatibility in mice. However, the high hydrophilicity and good water sorption characteristics of the PECH-AS film suggest that this brush polymer is better suited to applications requiring good biocompatibility and reduced chance of bacterial infection compared with the PECH-AP film." @default.
- W2332153973 created "2016-06-24" @default.
- W2332153973 creator A5002761078 @default.
- W2332153973 creator A5025527762 @default.
- W2332153973 creator A5048179208 @default.
- W2332153973 creator A5050439796 @default.
- W2332153973 creator A5051358508 @default.
- W2332153973 creator A5069736901 @default.
- W2332153973 creator A5070179898 @default.
- W2332153973 creator A5085698562 @default.
- W2332153973 creator A5088566653 @default.
- W2332153973 date "2011-05-27" @default.
- W2332153973 modified "2023-10-01" @default.
- W2332153973 title "Well-Defined DNA-Mimic Brush Polymers Bearing Adenine Moieties: Synthesis, Layer-by-Layer Self-Assembly, and Biocompatibility" @default.
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