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- W2332275157 abstract "Objective:To study the expression and significance of NUMB in oral leukoplakia and squamous cell carcinoma.Methods:The expressions of NUMB was detected by immunohistochemistry in 88 cases of tissues embeded in paraffin including normal oral epithelia and oral leukoplakia and squamous cell carcinoma.Results:The expression of NUMB in oral normal mucosa(95.7%),oral leukoplakia(75%) and oral squamous cell carcinoma(4.7%) were positive,but its expression was in order of decreasing frequency.NUMB in each group has a significant difference in the rate of positive expression(P0.05).Conclusions:The trend of NUMB positive expression rate increasing with the malignant degree of oral tissues suggested that the gene may be play a role in oral normal mucosa to the oral leukoplakia and then to oral squamous cell carcinoma.NUMB may become one of the hallmarks of early detection of cancer." @default.
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- W2332275157 date "2010-01-01" @default.
- W2332275157 modified "2023-09-25" @default.
- W2332275157 title "The expression and significance of NUMB in oral leukoplakia and squamous cell carcinoma" @default.
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