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- W2332346809 abstract "Immunology & Cell BiologyVolume 70, Issue 3 p. 159-171 Autoimmunity: Paradigms of Burnet and complexities of today IAN R. MACKAY, IAN R. MACKAY Centre For Molecular Biology and Medicine, Monash University, Melbourne, Victoria, AustraliaSearch for more papers by this author IAN R. MACKAY, IAN R. MACKAY Centre For Molecular Biology and Medicine, Monash University, Melbourne, Victoria, AustraliaSearch for more papers by this author First published: June 1992 https://doi.org/10.1038/icb.1992.21Citations: 7 Ian R. Mackay, Centre for Molecular Biology and Medicine, Monash University, Clayton, Vic. 3168, Australia. Presented as the Burner Oration of the Australian Society for Immunology, December 1991. AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat Reference 1 Fenner, F. 1987. Frank Macfarlane Burnet 1898–1985. Burnet Royal Society Memoirs. 2 Mackay, I. R. 1991. The ‘Burnet era’ of Immunology: Origins and influence. Immunol. Cell Biol. 69: 301–305. 3 Medawar, P. B. 1969. The genetic improvement of man. Australas. Ann. Med. 4: 317–320. 4 Burnet, F. M. 1948. The bases of allergic disease. Med. J. Aust. i: 57–63. 5 Burnet, F. M. 1971. Walter and Eliza Hall Institute 1915–1965. Melbourne University Press, Melbourne, p. 198. 6 Gear, J. S. 1946. Autoantigens and autoantibodies in the pathogenesis of disease with special reference to blackwater lever. Trans. Roy. Soc. Trop. Med. Hyg. 39: 301–314. 7 Joske, R. A. and King, W. E. 1955. The L.E. Cell phenomenon in active chronic viral hepatitis. Lancet ii: 477–480. 8 Mackay, I. R., Taft L. I. and Cowling D. C. 1956. Lupoid hepatitis. Lancet ii: 1323–1326. 9 Mackay, I. R. and Gajdusek D. C. 1958. An ‘autoimmune’ reaction against human tissue antigens in certain acute and chronic diseases. II. Clinical correlations. Arch. Intern. Med. 101: 30–46. 10 Mackay, I. R. 1956. Macroglobulinaemia. Australas. Ann. Med. 5: 245–253. 11 Burnet F. M. 1959. The Clonal Selection of Acquired Immunity. Cambridge University Press, London pp. 1–209. 12 Jerne, N. K. 1955. The natural selection theory of antibody production Proc. Natl Acad. Sci. USA. 41: 849–857. 13 Talmage, D. W. 1957. Allergy and immunology. Ami. Rev. Med. 8: 239–256. 14 Cotterell, G. 1961. N.Y.J. Am. September 22. 15 Mackay I. R. and Burnet F. M. 1963. Autoimmune Disease. Thomas, Springfield, pp. 1–323. 16 Rowley, M. J., Mackay, I. R., Chen, Q-Y., Knowles, W. J. and Zimmet, P. 1992. Antibodies to glutamic acid decarboxylase discriminate major types of diabetes mellitus. Diabetes (in press). 17 Warner N. L., Szenberg, A and Burnet, F. M. 1962. The immunological role of different lymphoid organs in the chicken. I. Dissociation of immunological responsiveness. Aust. J. Exp. Biol. Med. Sci. 40: 373–387. 18 Burnet, F. M. 1972. Autoimmunity and Autoimmune Disease. Medical and Technical Publishing. Lancaster, pp. 1–243. 19 Bielschowsky, M., Helyer, B. J. and Howie, J. B. 1959. Spontaneous haemolytic anaemia in mice of the NZB/B1 strain. Proc. Univ. Otago Med. Sch. 37: 9. 20 Holmes M. C. and Burnet F. M. 1964. The inheritance of autoimmune disease in mice: A study of hybrids of the strain NZB and C3H. Heredity 14: 419–434. 21 Burnet, F. M. and Holmes, M. 1962. Thymic lesions in autoimmune disease of mice. Nature 194: 146–147. 22 Russell P. J., Hicks, J. D. and Burnet F. M. 1966. Cyclophosphamide treatment of kidney disease in (NZB × NZW) F1 mice. Lancet i: 1279–1284. 23 McCune W. J., Golhus, J., Zeldes, W., Bohlke, P., Dunne, R. and Fox, D. A. 1988. Clinical and immunological effects of monthly administration of intravenous cyclophosphamide in severe systemic lupus erythematosus. N. Engl. J. Med. 318: 1423–1431. 24 Burnet, F. M. and Holmes, M. 1949. Some aspects of the epidemiology of poliomyelitis Proc. Roy. Australas. Coll. Physic. 4: 95–100. 25 Burnet, F. M. 1961. The new approach to immunology. N Engl. J. Med. 264: 24–34. 26 Burnet, F. M. 1966. Men or molecules. A tilt at molecular biology. Lancet i: 37–39. 27 Keating J. J., O'Brien, C. J., Stellon, A. J. et al 1987. Influence of aetiology, clinical and histological features on survival in chronic active hepatitis. An analysis of 204 patients. Quart. J. Med. 62: 59–66. 28 Burnet, F. M. 1972. Immunology as a scholarly discipline. Keynote address, First International Congress of Immunology, Washington. 1971. Perspect. Biol. Med. 16: 1–10. 29 Benacerraf, B. 1991. When all is said and done.. Ann. Rev. Immunol. 9: 1–26. 30 Sexton, C. 1991. The Seeds of Time. A life of Sir Macfarlane Burnet. Oxford University Press, Melbourne, p 16. 31 Mackay, I. R. and Rose N. R. 1992. Horizons. In The Autoimmune Diseases II, N. R. Rose and I. R. Mackay (eds). Academic Press, Orlando, pp. 409–430. 32 Banga, J. P. and McGregor, A. M. 1991. Enzymes as targets for autoantibodies in human autoimmune disease — Relevance to pathogenesis. Autoimmunity 9: 177–182. 33 Rowley, M. J., Maeda, T., Mackay, I. R. et al. 1992. Differing epitope selection of natural and induced antibodies to an autoantigen, the E2 subunit of pyruvate dehydrogenase complex PDC-E2: Relevance to the liver disease primary biliary cirrhosis (submitted). 34 Horsfall, A. C., Hay, F. C., Soltys, A. J. and Jones, M. G. 1991. Epitope mapping. Immunol. Today 12: 211–213. 35 Rolink, A. and Melchers, F. 1991. Molecular and cellular origins of B lymphocyte diversity. Cell 66: 1081–1094. 36 Shlomchik, M., Mascelli, M., Shan, H., et al. 1990. Anti-DNA antibodies from autoimmune mice arise by clonal expansion and somatic mutation. J. Exp. Med. 171: 265–297. 37 Friedman, D. F., Cho, E. A., Goldman, J. et al. 1991. The role of clonal selection in the pathogenesis of an autoreactive human B cell lymphoma. J. Exp. Med. 174: 525–537. 38 Zinkernagel, R. M. and Doherty, P. C. 1979. MHC-restricted cytotoxic T cells: Studies on the biological role of polymorphic major transplation antigens determining T cell restriction specificity, function and responsiveness. Adv. Immunol. 27: 52–177. 39 Burnet, F. M. 1967. Concepts of autoimmune disease and their implications for therapy. In: Reflections on Research and the Future of Medicine. C. E. Lyght (ed). McGraw-Hill, New York, pp. 9–28. 40 Kappler, J., Roehm, N. and Marrack, P. 1987. T cell tolerance by clonal elimation in the thymus. Cell 49: 273–280. 41 Akashi T and Eishi, Y. 1991. Developmental expression of autoimmune target antigens during organogenesis. Immunology 74: 524–533. 42 Gershon, R. K. and Kondo, K. 1971. Infectious immunological tolerance. Immunology 21: 903–914. 43 Nossal G. J. V. and Pike, B. L. 1980. Clonal anergy; Persistence in tolerant mice of antigen-binding B lymphocytes incapable of responding to antigen or mitogen. Proc. Natl Acad. Sci. USA 77: 1602–1606. 44 Sprent, L., Schaefer, M., Hurd, M., Surh, C. D. and Ron, Y. Matutc murine B and T cells transferred to SCID mice survive indefinitely and many maintain a virgin phenotype. J. Exp. Med. 174: 717–728. 45 Miller, J. F. A. P. and Morahan, G. 1992. Peripheral T cell tolerance. Ami. Rev. Immunol. 10: 51–69. 46 Fowell, D., McKnight, A. J., Powrie, F., Dyke, R. and Mason, D. 1991. Subsets of CD4+ T cells and their roles in the induction and prevention of autoimmunity. Immunol. Rev. 123: 37–64. 47 Burnet, F. M. 1985. Foreword. In The Autoimmune Diseases. N. R. Rose and I. R. Mackay (eds). Academic Press, Orlando, pp. xvii–xxi. 48 Bernard, C. C. A., Mandel, T. and Mackay, I. R. 1992. Experimental models of human autoimmune disease: Overview and prototypes. In The Autoimmune Diseases II. N. R. Rose and I. R. Mackay (eds). Academic Press. Orlando, pp. 47–106. 49 Paliard, X., West, S. G., Lafferty, J. A. et al. 1991. Evidence for the effects of a super-antigen in rheumatoid arthritis. Science 253: 325–329. 50 Ziff, M. 1991. Role of the endothelium in chronic inflammatory synovitis. Arthritis Rheum. 34: 1345–1352. 51 Mackay, C. R. 1992. Migration pathways and immunological memory among T lymphocytes. Sem. Immunol. 4: 51–58. 52 Strickland, R. G. and Mackay, I. R. 1973. A reappraisal of the nature and significance of chronic atrophic gastritis. Am. J. Dig. Dis. 18: 426–440. 53 Fong, T-L., Dooley, C. P. Dehesa, M. et al. 1991. Helicobacter pyloric infection in pernicious anemia: A prospective controlled study. Gastroenterology 100: 328–332. 54 Goldman, M., Druet, P. and Gleichmann, E. 1991. TH2 cells in systemic autoimmunity: Insights from allogeneic diseases and chemically-induced autoimmunity. Immunol. Today 12: 223–227. 55 J. M. W. Turner 18351840. Val d'Aosta (incomplete portrait). National Gallery of Victoria, Melbourne, Australia. Citing Literature Volume70, Issue3June 1992Pages 159-171 Journal of the Australian and New Zealand Society for Immunology ReferencesRelatedInformation" @default.
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