Matches in SemOpenAlex for { <https://semopenalex.org/work/W2332367322> ?p ?o ?g. }
Showing items 1 to 70 of
70
with 100 items per page.
- W2332367322 endingPage "69" @default.
- W2332367322 startingPage "41" @default.
- W2332367322 abstract "Chronic toxicity study of halopredone acetate (THS-201), a synthetic corticosteroid, was carried out using Jcl : Wistar rats. THS-201 was subcutaneously administered to the rat in doses of 0.02, 0.1, 0.5 and 2.5mg/kg/day, with the periods for administration and recovery being 12 and 2 months, respectively. In the group of THS-201 2.5 mg/kg, the below findings were observed :thinning of lumbar hair, suppression in body weight gain, decrease of food consumption in both sexes and decrease of water consumption in male. The lesions to lymphatic system were indicated by the examinations of hemogram, organ weight and histopathology. A few changes in urinary and biochemical values were seen, and foreign body granuloma was observed in the injected subcutis. After 2 month-recovery period, above-mentioned findings almost disappeared. In the group of THS-201 0.5mg/kg, some of the changes were noted slightly and disappeared after the recovery period. IN the groups of THS-201 0.1 and 0.02mg/kg, any toxic changes attrib-utable to THS-201 were not observed. It was concluded that the non-toxic does and the defined toxic dose of THS-201 in this study were 0.1 and 0.5 mg/kg/day, respectively." @default.
- W2332367322 created "2016-06-24" @default.
- W2332367322 creator A5006612530 @default.
- W2332367322 creator A5007342445 @default.
- W2332367322 creator A5020097279 @default.
- W2332367322 creator A5035504261 @default.
- W2332367322 creator A5056589260 @default.
- W2332367322 creator A5061163662 @default.
- W2332367322 creator A5086435720 @default.
- W2332367322 date "1985-01-01" @default.
- W2332367322 modified "2023-10-17" @default.
- W2332367322 title "STUDY ON TOXICITY OF HALOPREDONE ACETATE : (III) CHRONIC TOXICITY STUDY IN RATS" @default.
- W2332367322 cites W1535735195 @default.
- W2332367322 cites W1655193342 @default.
- W2332367322 cites W2134920613 @default.
- W2332367322 cites W2427054961 @default.
- W2332367322 cites W619562436 @default.
- W2332367322 doi "https://doi.org/10.2131/jts.10.supplementi_41" @default.
- W2332367322 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/4068062" @default.
- W2332367322 hasPublicationYear "1985" @default.
- W2332367322 type Work @default.
- W2332367322 sameAs 2332367322 @default.
- W2332367322 citedByCount "0" @default.
- W2332367322 crossrefType "journal-article" @default.
- W2332367322 hasAuthorship W2332367322A5006612530 @default.
- W2332367322 hasAuthorship W2332367322A5007342445 @default.
- W2332367322 hasAuthorship W2332367322A5020097279 @default.
- W2332367322 hasAuthorship W2332367322A5035504261 @default.
- W2332367322 hasAuthorship W2332367322A5056589260 @default.
- W2332367322 hasAuthorship W2332367322A5061163662 @default.
- W2332367322 hasAuthorship W2332367322A5086435720 @default.
- W2332367322 hasBestOaLocation W23323673221 @default.
- W2332367322 hasConcept C126322002 @default.
- W2332367322 hasConcept C142724271 @default.
- W2332367322 hasConcept C147583825 @default.
- W2332367322 hasConcept C29730261 @default.
- W2332367322 hasConcept C42407357 @default.
- W2332367322 hasConcept C53164099 @default.
- W2332367322 hasConcept C544855455 @default.
- W2332367322 hasConcept C71924100 @default.
- W2332367322 hasConceptScore W2332367322C126322002 @default.
- W2332367322 hasConceptScore W2332367322C142724271 @default.
- W2332367322 hasConceptScore W2332367322C147583825 @default.
- W2332367322 hasConceptScore W2332367322C29730261 @default.
- W2332367322 hasConceptScore W2332367322C42407357 @default.
- W2332367322 hasConceptScore W2332367322C53164099 @default.
- W2332367322 hasConceptScore W2332367322C544855455 @default.
- W2332367322 hasConceptScore W2332367322C71924100 @default.
- W2332367322 hasIssue "SupplementI" @default.
- W2332367322 hasLocation W23323673221 @default.
- W2332367322 hasLocation W23323673222 @default.
- W2332367322 hasOpenAccess W2332367322 @default.
- W2332367322 hasPrimaryLocation W23323673221 @default.
- W2332367322 hasRelatedWork W2054169229 @default.
- W2332367322 hasRelatedWork W2091632846 @default.
- W2332367322 hasRelatedWork W2142720516 @default.
- W2332367322 hasRelatedWork W2188878844 @default.
- W2332367322 hasRelatedWork W2332367322 @default.
- W2332367322 hasRelatedWork W2366349377 @default.
- W2332367322 hasRelatedWork W2381951770 @default.
- W2332367322 hasRelatedWork W2428545646 @default.
- W2332367322 hasRelatedWork W3080746311 @default.
- W2332367322 hasRelatedWork W3190780457 @default.
- W2332367322 hasVolume "10" @default.
- W2332367322 isParatext "false" @default.
- W2332367322 isRetracted "false" @default.
- W2332367322 magId "2332367322" @default.
- W2332367322 workType "article" @default.