FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2332623206> ?p ?o ?g. }

• W2332623206 endingPage "10642" @default.
• W2332623206 startingPage "10632" @default.
• W2332623206 abstract "The aim of this study was to investigate the influence of atorvastatin on the opening of the mitochondrial permeability transition pore (MPTP) and the expression of cytochrome C (Cyt C) in Sprague-Dawley rats with cerebral ischemia-reperfusion (I/R). The rat model of cerebral artery ischemia was established by the suture-occluded method with ischemia for 2 h and reperfusion for 72 h. Thirty-four male rats were randomly divided into four groups: the normal group and the sham-operation group without any treatment, the I/R group with only intragastric administration of normal saline, and the intervention group, which received intragastric administration of 10 mg/kg atorvastatin at different times. All rats were sacrificed at 72 h. Compared with the I/R group, the morphology of nerve cells in the intervention group was reduced, the number of TUNEL-positive cells decreased, the expression of cortical cytoplasm Cyt C decreased, and the mitochondrial absorbance value increased. All of these differences were statistically significant. Atorvastatin could inhibit neuronal apoptosis and alleviate the cerebral I/R injury. The mechanism may be related to the blocking of the MPTP opening and the subsequent reduction of Cyt C release." @default.
• W2332623206 created "2016-06-24" @default.
• W2332623206 creator A5007871922 @default.
• W2332623206 creator A5042957245 @default.
• W2332623206 creator A5067125955 @default.
• W2332623206 creator A5085891147 @default.
• W2332623206 date "2014-01-01" @default.
• W2332623206 modified "2023-10-17" @default.
• W2332623206 title "Protection effect of atorvastatin in cerebral ischemia-reperfusion injury rats by blocking the mitochondrial permeability transition pore" @default.
• W2332623206 cites W139494526 @default.
• W2332623206 cites W1492482999 @default.
• W2332623206 cites W1839071809 @default.
• W2332623206 cites W1986927401 @default.
• W2332623206 cites W1987126302 @default.
• W2332623206 cites W1998696969 @default.
• W2332623206 cites W2000605323 @default.
• W2332623206 cites W2002555098 @default.
• W2332623206 cites W2006466939 @default.
• W2332623206 cites W2007026386 @default.
• W2332623206 cites W2012582908 @default.
• W2332623206 cites W2020178087 @default.
• W2332623206 cites W2052929275 @default.
• W2332623206 cites W2058217541 @default.
• W2332623206 cites W2119683782 @default.
• W2332623206 cites W2155259839 @default.
• W2332623206 cites W2335261857 @default.
• W2332623206 cites W272299298 @default.
• W2332623206 doi "https://doi.org/10.4238/2014.december.18.5" @default.
• W2332623206 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/25526184" @default.
• W2332623206 hasPublicationYear "2014" @default.
• W2332623206 type Work @default.
• W2332623206 sameAs 2332623206 @default.
• W2332623206 citedByCount "20" @default.
• W2332623206 countsByYear W23326232062015 @default.
• W2332623206 countsByYear W23326232062016 @default.
• W2332623206 countsByYear W23326232062017 @default.
• W2332623206 countsByYear W23326232062018 @default.
• W2332623206 countsByYear W23326232062019 @default.
• W2332623206 countsByYear W23326232062020 @default.
• W2332623206 countsByYear W23326232062021 @default.
• W2332623206 countsByYear W23326232062022 @default.
• W2332623206 countsByYear W23326232062023 @default.
• W2332623206 crossrefType "journal-article" @default.
• W2332623206 hasAuthorship W2332623206A5007871922 @default.
• W2332623206 hasAuthorship W2332623206A5042957245 @default.
• W2332623206 hasAuthorship W2332623206A5067125955 @default.
• W2332623206 hasAuthorship W2332623206A5085891147 @default.
• W2332623206 hasBestOaLocation W23326232061 @default.
• W2332623206 hasConcept C126322002 @default.
• W2332623206 hasConcept C134018914 @default.
• W2332623206 hasConcept C13591479 @default.
• W2332623206 hasConcept C137183658 @default.
• W2332623206 hasConcept C185592680 @default.
• W2332623206 hasConcept C190283241 @default.
• W2332623206 hasConcept C196795494 @default.
• W2332623206 hasConcept C2777482532 @default.
• W2332623206 hasConcept C2778674702 @default.
• W2332623206 hasConcept C2780114680 @default.
• W2332623206 hasConcept C29311851 @default.
• W2332623206 hasConcept C31573885 @default.
• W2332623206 hasConcept C42219234 @default.
• W2332623206 hasConcept C513476851 @default.
• W2332623206 hasConcept C541997718 @default.
• W2332623206 hasConcept C55493867 @default.
• W2332623206 hasConcept C71924100 @default.
• W2332623206 hasConcept C98274493 @default.
• W2332623206 hasConceptScore W2332623206C126322002 @default.
• W2332623206 hasConceptScore W2332623206C134018914 @default.
• W2332623206 hasConceptScore W2332623206C13591479 @default.
• W2332623206 hasConceptScore W2332623206C137183658 @default.
• W2332623206 hasConceptScore W2332623206C185592680 @default.
• W2332623206 hasConceptScore W2332623206C190283241 @default.
• W2332623206 hasConceptScore W2332623206C196795494 @default.
• W2332623206 hasConceptScore W2332623206C2777482532 @default.
• W2332623206 hasConceptScore W2332623206C2778674702 @default.
• W2332623206 hasConceptScore W2332623206C2780114680 @default.
• W2332623206 hasConceptScore W2332623206C29311851 @default.
• W2332623206 hasConceptScore W2332623206C31573885 @default.
• W2332623206 hasConceptScore W2332623206C42219234 @default.
• W2332623206 hasConceptScore W2332623206C513476851 @default.
• W2332623206 hasConceptScore W2332623206C541997718 @default.
• W2332623206 hasConceptScore W2332623206C55493867 @default.
• W2332623206 hasConceptScore W2332623206C71924100 @default.
• W2332623206 hasConceptScore W2332623206C98274493 @default.
• W2332623206 hasIssue "4" @default.
• W2332623206 hasLocation W23326232061 @default.
• W2332623206 hasLocation W23326232062 @default.
• W2332623206 hasOpenAccess W2332623206 @default.
• W2332623206 hasPrimaryLocation W23326232061 @default.
• W2332623206 hasRelatedWork W2049043910 @default.
• W2332623206 hasRelatedWork W2091851917 @default.
• W2332623206 hasRelatedWork W2168294277 @default.
• W2332623206 hasRelatedWork W2332623206 @default.
• W2332623206 hasRelatedWork W2348294111 @default.
• W2332623206 hasRelatedWork W2358367149 @default.
• W2332623206 hasRelatedWork W2408000122 @default.
• W2332623206 hasRelatedWork W2613290991 @default.
• W2332623206 hasRelatedWork W2887790555 @default.

• next